Study Detail

TitleCRISPRKO_screen_to_investigate_resistance_to_NK_cell
Study TypeCancer Genomics
Abstract We aim to identify novel mechanisms by which cancer cells can escape from NK cell mediated killing by performing genome wider CRISPR screens. NK sensitive K562 cells were transduced with the Yusa v1.1 CRISPR genome-wide KO library and after expansion paired samples were subjected to killing by an NK .. [more]
Description NK sensitive K562 cells were transduced with the Yusa v1.1 CRISPR genome-wide KO library and after expansion paired samples were subjected to killing by an NK cell line, NK92.
Center NameWellcome Sanger Institute