Study Detail

TitleKeratinocyte expression of Mcpip1 is essential for the maintenance of skin integrity and for the control of local and systemic inflammation
Study TypeOther
Abstract MCPIP1 (Regnase-1, encoded by the ZC3H12A gene) regulates the mRNA stability of several inflammatory cytokines. Due to the critical role of this RNA endonuclease in the suppression of inflammation, Mcpip1 deficiency in mice leads to the development of postnatal multiorgan inflammation and premature .. [more]
Description MCPIP1 (Regnase-1, encoded by the ZC3H12A gene) regulates the mRNA stability of several inflammatory cytokines. Due to the critical role of this RNA endonuclease in the suppression of inflammation, Mcpip1 deficiency in mice leads to the development of postnatal multiorgan inflammation and premature .. [more]
Center NameCentrum Medyczne Ksztalcenia Podyplomowego