Study Detail

TitleATAC-seq of primary mammalian aortic endothelial cells before and after TNFa stimulation
Study TypeOther
Abstract To identify conserved TNFa-induced changes in chromatin-accessibility in mammals, we performed ATAC-seq in primary vascular endothelial cells (ECs) isolated from the aortas of human (HAEC), mouse (MAEC) and cow (BAEC), before and after TNFa. We overlay our data with multi-species NF-?B binding data .. [more]
Description To identify conserved TNFa-induced changes in chromatin-accessibility in mammals, we performed ATAC-seq in primary vascular endothelial cells (ECs) isolated from the aortas of human (HAEC), mouse (MAEC) and cow (BAEC), before and after TNFa. We overlay our data with multi-species NF-?B binding data .. [more]
Center NameThe Hospital for Sick Children, Genetics and Genome Biology University of Toronto, Department of Molecular Genetics