Study Detail

TitleB cell humoral response and differentiation is regulated by non-canonical poly(A) polymerase TENT5C.
Study TypeOther
Abstract The goal of this study was to assess changes in the activated B cells transcriptome upon TENT5C knockout in mice. Primary B cells were isolated from either wild-type or TENT5C KO mice then activated in vitro with 20 ng/ml IL-4 (Peprotech) and 20 ??g/ml LPS (Santa Cruz) for 7 days. RNA isolation was .. [more]
Description The goal of this study was to assess changes in the activated B cells transcriptome upon TENT5C knockout in mice. Primary B cells were isolated from either wild-type or TENT5C KO mice then activated in vitro with 20 ng/ml IL-4 (Peprotech) and 20 ??g/ml LPS (Santa Cruz) for 7 days. RNA isolation was .. [more]
Center NameINSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS, POLISH ACADEMY OF SCIENCES