Study Detail

TitleModulation of NF-kB-Dependent Gene Transcription Using Programmable DNA Minor Groove Binders
Study TypeOther
Abstract Nuclear factor kappaB (NF-kB) is a transcription factor that regulates various aspects of immune response, cell death and differentiation as well as cancer. In this study we introduce the Py-Im polyamide 1 that binds preferentially to the sequences 5''-WGGWWW-3'' and 5'' GGGWWW-3''. The compound is .. [more]
Center NameGEO