Study Detail

TitleGenome-wide profiling of LXR, RXR and PPARa in mouse liver reveals extensive sharing of binding sites
Study TypeOther
Abstract The liver X receptors (LXRs) are nuclear receptors that form permissive heterodimers with retinoid X receptor (RXR) and are important regulators of lipid metabolism in the liver. We have recently shown that RXR agonist-induced hypertriglyceridemia and hepatic steatosis in mice is dependent on LXR an .. [more]
Center NameGEO