Study Detail

TitleTargeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme
Study TypeWhole Genome Sequencing
Abstract Zinc-finger nucleases (ZFNs) drive highly efficient genome editing by generating a site-specific DNA double-strand break (DSB) at a predetermined site in the genome. Subsequent repair of this break via the non-homologous end-joining (NHEJ) or homology-directed repair (HDR) pathways results in target .. [more]
Description
Center NameSangamo Biosciences Inc.