Study Detail

TitleInvestigation of DNA polymorphisms in the cerebellar abiotrophy region in Australian Kelpie dogs
Study TypeWhole Genome Sequencing
Abstract Cerebellar Abiotrophy (CA) is an autosomal recessive disease in Australian kelpie dogs that results in ataxia. The disease locus was previously mapped to a 5 Mb region on canine chromosome 3. Nimblegen sequence capture and 454-sequencing of this 5 Mb candidate region was performed for two affected a .. [more]
Description Cerebellar Abiotrophy (CA) is an autosomal recessive disease in Australian kelpie dogs that results in ataxia. The disease locus was previously mapped to a 5 Mb region on canine chromosome 3 (Shearman et al 2011, Animal Genetics). Nimblegen sequence capture and 454-sequencing of this 5 Mb candidate .. [more]
Center NameNational Centre for Genetic Engineering and Biotec