Study Detail

TitleCell-autonomous function of Runx1 transcriptionally regulates megakaryocytic maturation in mice (ChIP-seq)
Study TypeOther
Abstract RUNX1 transcription factor (TF) is a key regulator of megakaryocytic development and when mutated is associated with familial platelet disorder and predisposition to acute myeloid leukemia (FPD-AML). We used mice lacking Runx1 specifically in megakaryocytes (MKs) to characterize the Runx1-mediated t .. [more]
Description
Center NameGEO