Study Detail

TitleGenome-wide mapping of ssDNA in mouse
Study TypeWhole Genome Sequencing
Abstract We combined chemical and enzymatic techniques to map single-stranded DNA (ssDNA) across the mammalian genome by high-throughput sequencing (ssDNA-Seq). The new approach makes use of KMnO4 treatment, which modifies ssDNA in living cells by oxidizing pyrimidine bases with a marked preference for expos .. [more]
Center NameBioProject