Study Detail

TitleRetroelements and DUX4 Create Primate-specific Promoters for Germline Genes
Study TypeTranscriptome Analysis
Abstract The human double-homeodomain retrogene DUX4 is normally expressed at high levels in germ cells of the testis. When aberrantly expressed in muscle its protein product causes facioscapulohumeral muscular dystrophy (FSHD), perhaps partly by inducing inappropriate expression of germline genes. DUX4 can .. [more]
Description
Center NameGEO