Study Detail

TitleTranslation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3’ UTRs
Study TypeOther
Abstract The RNA helicase UPF1 is best known for its key function in mRNA nonsense-mediated mRNA decay (NMD), but has also been implicated in additional mRNA turnover mechanisms, telomere homeostasis, and DNA replication. In NMD, UPF1 recruitment to target mRNAs is thought to occur through interaction with r .. [more]
Description
Center NameGEO