Study Detail

TitleCHD5 is required for neurogenesis and has a dual role in facilitating gene expression and Polycomb gene repression
Study TypeOther
Abstract The chromatin remodeler CHD5 is expressed in neural tissue and is frequently deleted in aggressive neuroblastoma. Very little is known about the function of CHD5 in the nervous system or its mechanism of action. Here we report that depletion of Chd5 in the developing murine neocortex blocks neuronal .. [more]
Description
Center NameGEO