Study Detail

TitleFOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis
Study TypeOther
Abstract FOXO transcription factors are central regulators of longevity from worms to humans. FOXO3 – the FOXO isoform associated with exceptional human longevity – preserves adult neural stem cell pools. Here we identify FOXO3 direct targets genome-wide in primary cultures of adult neural progenitor cells ( .. [more]
Center NameGEO