Study Detail

TitleLiver Med23 ablation improves glucose and lipid metabolism and prevent diet-induced obesity
Study TypeTranscriptome Analysis
Abstract Mediator complex function as an integrative hub for transcriptional regulation. Here we show that Mediator subunit MED23 regulate glucose and lipid metabolism via FOXO1 in liver. Here, we have generated a liver-specific Med23-knockout (LMKO) mouse and found that Med23-deletion in liver improved gluc .. [more]
Center NameGEO