Study Detail

TitleRNA-sequencing of Nedd4+/+ and Nedd4-/- mouse splenic B cells
Study TypeTranscriptome Analysis
Abstract Programmed mutagenesis of the immunoglobulin locus of B-lymphocytes during class switch recombination and somatic hypermutation requires RNA polymerase II (RNA polII) transcription complex dependent targeting of the DNA mutator, Activation Induced cytidine Deaminase (AID). AID deaminates cytidine re .. [more]
Center NameGEO