Study Detail

TitleGenetic and molecular basis of drug resistance and species-specific drug action in Schistosome parasites
Study TypeTranscriptome Analysis
Abstract Oxamniquine resistance evolved in the human blood fluke (Schistosoma mansoni) in Brazil in the 1970s. We crossed parental parasites differing ~500-fold in drug response, determined drug sensitivity and marker segregation in clonally-derived F2s, and identified a single QTL (LOD=31) on chromosome 6. .. [more]
Center NameGEO