Study Detail

TitlePremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [RRBS]
Study TypeOther
Abstract We report a reprogrammable mouse system in which reprogramming factor expression in vivo can be controlled temporally by treatment with doxycycline (Dox). Transient expression of reprogramming factors in vivo results in tumor development in various tissues, consisting of undifferentiated dysplastic .. [more]
Center NameGEO