Study Detail

TitleOverexpression of UHRF1 drives DNA hypomethylation and hepatocellular carcinoma
Study TypeTranscriptome Analysis
Abstract UHRF1 is an essential regulator of DNA methylation that is highly expressed in many cancers. Using transgenic zebrafish, cultured cells and human tumors, we demonstrate that UHRF1 is an oncogene. RNAseq was used to assess the variation in gene expression between control and experimental samples. Ove .. [more]
Center NameGEO