Study Detail

TitleGrhl3 is essential for epidermal barrier repair from both physical and immune injury, relevance to lesional skin disease
Study TypeOther
Abstract Epidermal barrier repair mechanisms activated in psoriasis lesions are likely involved in limiting the severity of this disease. We show that loss of grainyhead-like 3 (Grhl3), a pro-terminal differentiation factor in the epidermis, is sufficient to trigger greater sensitivity to and delayed resolut .. [more]
Description
Center NameGEO