Study: JGAS00000000077

Identifier

AccessionJGAS00000000077

Description

TitleRNA-seq analysis of BMP-stimulated glioma initiating cells
AbstractBone morphogenetic protein (BMP) signaling has been shown to suppress progression of glioblastoma by promoting astrocytic differentiation; however, roles of BMP signaling in cell proliferation and apoptosis of glioblastoma cells remains to be elucidated. We here performed RNA-seq analysis of glioma initiating cells to identify transcriptional target(s) of BMP.
Study Type
Study TypeTranscriptome Sequencing

Grant

Grant 1
TitleEffects of TGF-beta family on cancer microenvironment and strategies for cancer therapy
AgencyMinistry of Education, Culture, Sports, and Technology of Japan (MEXT)
Grant ID22112002
Grant 2
TitleRoles of BMP signaling in maintenance of cell stemness
AgencyJapan Society for the Promotion of Science (JSPS)
Grant ID24390070
Grant 3
TitleTranscriptional regulation by TGF-beta signaling and its relation to progression of cancer
AgencyJapan Society for the Promotion of Science (JSPS)
Grant ID15H05774
Grant 4
TitleGrants-in-Aid for Scientific Research
AgencyMinistry of Health, Labour and Welfare of Japan ()
Grant ID201220012
Grant 5
TitleCore-to-Core Program Cooperative International Framework in TGF-beta Family Signaling
AgencyJapan Society for the Promotion of Science (JSPS)
Grant ID
Grant 6
TitleEphA6 tyrosine kinase as a potential biomarker for BMP-based therapy in adult glioblastoma
AgencyJapan Society for the Promotion of Science (JSPS)
Grant ID19K16735
Grant 7
TitleMolecular mechanisms of cell differentiation and diversity by TGF-beta family members
AgencyJapan Society for the Promotion of Science (JSPS)
Grant ID17H06326

Publication

Publication 1
PubMed ID28459464
Publication Statuspublished
DB TypePUBMED
Publication 2
PubMed ID31483918
Publication Statuspublished
DB TypePUBMED

Study Attribute

NBDC Numberhum0088
Registration date2016-10-28
Submitting organizationUniversity of Tokyo
Principal InvestigatorKohei Miyazono
Molecular Data TypeRNA Sequencing
PlatformGenome Analyzer IIx
VendorIllumina
Comment
Molecular Data TypeRNA Sequencing
PlatformIon Proton
VendorThermo Fisher Scientific
Comment
Primary PhenotypeCancer
Disease TypeNeoplasms
Dataset
Accession Title Dataset type Data objects Policy
JGAD00000000077 RNA-seq analysis of BMP-stimulated glioma initiating cells Transcriptome profiling by high-throughput sequencing 4 JGAP00000000001
JGAD00000000263 RNA-seq analysis of BMP-stimulated glioma initiating cells Transcriptome profiling by high-throughput sequencing 6 JGAP00000000001