Study: JGAS00000000136

Identifier

AccessionJGAS00000000136

Description

TitleResearch for drug discovery and elucidation of pathophysiology using disease-specific iPS cells
AbstractWe investigated roles of KRAS on stemness maintenance and differentiation propensity in the context of induced pluripotent stem cells (iPSCs) using isogenic KRAS mutant (G13C/WT) and wild-type (WT/WT) iPSCs from the same RAS-associated autoimmune lymphoproliferative syndrome-like disease (RALD) patients. Exome-seq analysis was conducted to compare gene profiles of WT/WT and G13C/WT iPS cells. We have not found any differences of gene mutation in the two genotypes.
Study Type
Study TypeExome Sequencing

Study Attribute

NBDC Numberhum0139
Registration date2018-05-29
Submitting organizationThe University of Tokyo
Principal InvestigatorMakoto Otsu
Molecular Data TypeExome Sequencing
PlatformHiSeq 1500
VendorIllumina
Comment
Dataset
Accession Title Dataset type Data objects Policy
JGAD00000000205 iPSC from RALD patient Exome sequencing 2 JGAP00000000001