<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<STUDY_SET>
    <STUDY accession="DRP002384" center_name="UT-AQUA" alias="DRP002384">
        <IDENTIFIERS>
            <PRIMARY_ID label="BioProject ID">PRJDB3068</PRIMARY_ID>
        </IDENTIFIERS>
        <DESCRIPTOR>
            <STUDY_TITLE>Dramatic improvement in genome assembly by using doubled-haploid individuals</STUDY_TITLE>
            <STUDY_TYPE existing_study_type="Other"/>
            <STUDY_ABSTRACT>Here, we improved draft genome sequence quality by employing doubled-haploid individuals. We sequenced wildtype and doubled-haploid Takifugu rubripes genomes, under the same conditions, using the Illumina platform and assembled contigs with SOAPdenovo2. We observed 5.4-fold and 2.6-fold improvement in the sizes of the N50 contig and scaffold of doubled-haploid individuals, respectively, compared to the wildtype, indicating that the use of a doubled-haploid genome aids in accurate genome analysis.</STUDY_ABSTRACT>
            <CENTER_PROJECT_NAME>Dramatic improvement in genome assembly by using doubled-haploid individuals</CENTER_PROJECT_NAME>
            <RELATED_STUDIES>
                <RELATED_STUDY>
                    <RELATED_LINK>
                        <DB>bioproject</DB>
                        <ID>PRJDB3068</ID>
                        <LABEL>PRJDB3068</LABEL>
                    </RELATED_LINK>
                    <IS_PRIMARY>true</IS_PRIMARY>
                </RELATED_STUDY>
            </RELATED_STUDIES>
            <STUDY_DESCRIPTION>Here, we improved draft genome sequence quality by employing doubled-haploid individuals. We sequenced wildtype and doubled-haploid Takifugu rubripes genomes, under the same conditions, using the Illumina platform and assembled contigs with SOAPdenovo2. We observed 5.4-fold and 2.6-fold improvement in the sizes of the N50 contig and scaffold of doubled-haploid individuals, respectively, compared to the wildtype, indicating that the use of a doubled-haploid genome aids in accurate genome analysis.</STUDY_DESCRIPTION>
        </DESCRIPTOR>
    </STUDY>
</STUDY_SET>
