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<STUDY_SET>
    <STUDY alias="DRP003353" center_name="KYUSH-MIB" accession="DRP003353">
        <IDENTIFIERS>
            <PRIMARY_ID label="BioProject ID">PRJDB3148</PRIMARY_ID>
        </IDENTIFIERS>
        <DESCRIPTOR>
            <STUDY_TITLE>Transcriptome analysis of oncogene induced transformation in human diploid fibroblasts (TIG-3)</STUDY_TITLE>
            <STUDY_TYPE existing_study_type="Other"/>
            <STUDY_ABSTRACT>To estimate the impact of oncogenesis on transcriptome, we established cell lines as cellular oncogenic models induced by combinations of oncogenes using human lung diploid fibroblasts (HDFs: TIG-3). We performed transcriptome analysis of TIG-3 (parental), TIG-3 TS (hTert/SV40, immortalized), TIG-TSM (hTert/SV40/c-Myc transformed) and TIG-TSM (hTert/SV40/c-Myc transformed).</STUDY_ABSTRACT>
            <CENTER_PROJECT_NAME>Transcriptome analysis of oncogene induced transformation in human diploid fibroblasts (TIG-3)</CENTER_PROJECT_NAME>
            <RELATED_STUDIES>
                <RELATED_STUDY>
                    <RELATED_LINK>
                        <DB>bioproject</DB>
                        <ID>PRJDB3148</ID>
                        <LABEL>PRJDB3148</LABEL>
                    </RELATED_LINK>
                    <IS_PRIMARY>true</IS_PRIMARY>
                </RELATED_STUDY>
            </RELATED_STUDIES>
            <STUDY_DESCRIPTION>To estimate the impact of oncogenesis on transcriptome, we established cell lines as cellular oncogenic models induced by combinations of oncogenes using human lung diploid fibroblasts (HDFs: TIG-3). We performed transcriptome analysis of TIG-3 (parental), TIG-3 TS (hTert/SV40, immortalized), TIG-TSM (hTert/SV40/c-Myc transformed) and TIG-TSM (hTert/SV40/c-Myc transformed).</STUDY_DESCRIPTION>
        </DESCRIPTOR>
    </STUDY>
</STUDY_SET>
