<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY accession="ERP109473" alias="E-MTAB-6932" broker_name="ArrayExpress" center_name="EMBL-European Bioinformatics Institute">
    <IDENTIFIERS>
      <PRIMARY_ID>ERP109473</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject">PRJEB27399</EXTERNAL_ID>
      <SUBMITTER_ID namespace="EMBL-European Bioinformatics Institute">E-MTAB-6932</SUBMITTER_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>CUT&amp;RUN chromatin profiling of H3K4me3 and H3K9me3 histone marks in spermatids and spermatocytes</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>Spermatogenesis is a recurring differentiation process that results in the production of male gametes within the testes. During this process, spermatogonial stem cells differentiate to form spermatocytes, which undergo two rounds of meiotic division to form haploid spermatids. Throughout spermiogenesis, round spermatids elongate to form mature sperm. To profile changes in chromatin marks between spermatocytes and spermatids, we generated CUT&amp;RUN data of H3K4me3 and H3K9me3 marks in sorted spermatocytes and spermatids.</STUDY_ABSTRACT>
      <STUDY_DESCRIPTION>Spermatogenesis is a recurring differentiation process that results in the production of male gametes within the testes. During this process, spermatogonial stem cells differentiate to form spermatocytes, which undergo two rounds of meiotic division to form haploid spermatids. Throughout spermiogenesis, round spermatids elongate to form mature sperm. To profile changes in chromatin marks between spermatocytes and spermatids, we generated CUT&amp;RUN data of H3K4me3 and H3K9me3 marks in sorted spermatocytes and spermatids.</STUDY_DESCRIPTION>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <URL_LINK>
          <LABEL>E-MTAB-6932 in ArrayExpress</LABEL>
          <URL>http://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-6932</URL>
        </URL_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
    <STUDY_ATTRIBUTES>
      <STUDY_ATTRIBUTE>
        <TAG>ENA-FIRST-PUBLIC</TAG>
        <VALUE>2019-01-25</VALUE>
      </STUDY_ATTRIBUTE>
      <STUDY_ATTRIBUTE>
        <TAG>ENA-LAST-UPDATE</TAG>
        <VALUE>2018-06-21</VALUE>
      </STUDY_ATTRIBUTE>
    </STUDY_ATTRIBUTES>
  </STUDY>
</STUDY_SET>
