<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY accession="ERP110353" alias="ena-STUDY-M.L.S.U.-11-08-2018-08:15:30:297-639" center_name="M.L.S.U.">
    <IDENTIFIERS>
      <PRIMARY_ID>ERP110353</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject">PRJEB28177</EXTERNAL_ID>
      <SUBMITTER_ID namespace="M.L.S.U.">ena-STUDY-M.L.S.U.-11-08-2018-08:15:30:297-639</SUBMITTER_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Isolation of lactobacilli was done using camel milk, probiotic properties such as bile tolerance, antibacterial activity and antibiotic resistance was done.</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Other"/>
      <STUDY_ABSTRACT>Lactic acid bacteria (LAB) possess probiotic potential and play a significant role to combat intestinal pathogens. The objective of the present investigation was to isolate, characterize and screen lactobacilli associated with camel milk for probiotic properties such as antibacterial activity, bile tolerance and antibiotic resistance. Among various isolates screened Lactobacillus plantarum CM114 showed remarkable antibacterial activity against B.cereus, B.subtilis, and E.coli in supernatant even after neutralization and protease treatment confirming bacteriocin activity. L. fermentum CM36 tolerated oxgall up to 0.3% (w/v) and showed resistance to various antibiotics used in the study.  L. fermentum CM114 showed potential for antibacterial and bile tolerance and may be further explored for its benefits towards animal and human health.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>Study of probiotic potential of lactobacilli</CENTER_PROJECT_NAME>
      <STUDY_DESCRIPTION>Lactic acid bacteria (LAB) possess probiotic potential and play a significant role to combat intestinal pathogens. The objective of the present investigation was to isolate, characterize and screen lactobacilli associated with camel milk for probiotic properties such as antibacterial activity, bile tolerance and antibiotic resistance. Among various isolates screened Lactobacillus plantarum CM114 showed remarkable antibacterial activity against B.cereus, B.subtilis, and E.coli in supernatant even after neutralization and protease treatment confirming bacteriocin activity. L. fermentum CM36 tolerated oxgall up to 0.3% (w/v) and showed resistance to various antibiotics used in the study.  L. fermentum CM114 showed potential for antibacterial and bile tolerance and may be further explored for its benefits towards animal and human health.</STUDY_DESCRIPTION>
    </DESCRIPTOR>
    <STUDY_ATTRIBUTES>
      <STUDY_ATTRIBUTE>
        <TAG>ENA-FIRST-PUBLIC</TAG>
        <VALUE>2018-09-10</VALUE>
      </STUDY_ATTRIBUTE>
      <STUDY_ATTRIBUTE>
        <TAG>ENA-LAST-UPDATE</TAG>
        <VALUE>2018-08-11</VALUE>
      </STUDY_ATTRIBUTE>
    </STUDY_ATTRIBUTES>
  </STUDY>
</STUDY_SET>
