ERP138707 PRJEB53892 E-MTAB-11878 Single-nucleotide variant and marker frequency analysis of Sinorhizobium meliloti strains with rearranged genomic DNA. S. meliloti strains with a bi- and monopartite genome configuration were constructed by consecutive Cre/lox-mediated site-specific fusions of the secondary replicons. Beside the correct genomic arrangements, these strains and precursors were tested for variations in the nucleotide sequence. Further, a marker frequency analysis was performed to test if replication is initiated at all origins and to determine the replication termination regions of the triple replicon fusion molecule. To gain the sequence data for these analyses, respective strains were applied to whole genome sequencing using an Illumina MiSeq-System. S. meliloti strains with a bi- and monopartite genome configuration were constructed by consecutive Cre/lox-mediated site-specific fusions of the secondary replicons. Beside the correct genomic arrangements, these strains and precursors were tested for variations in the nucleotide sequence. Further, a marker frequency analysis was performed to test if replication is initiated at all origins and to determine the replication termination regions of the triple replicon fusion molecule. To gain the sequence data for these analyses, respective strains were applied to whole genome sequencing using an Illumina MiSeq-System. E-MTAB-11878 in ArrayExpress http://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-11878 ENA-FIRST-PUBLIC 2022-10-10 ENA-LAST-UPDATE 2022-10-10