<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY accession="ERP139407" alias="66d4b043-ff04-4147-9551-059c073a475d" center_name="centre leon berard clb crcl">
    <IDENTIFIERS>
      <PRIMARY_ID>ERP139407</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject">PRJEB54579</EXTERNAL_ID>
      <SUBMITTER_ID namespace="centre leon berard clb crcl">66d4b043-ff04-4147-9551-059c073a475d</SUBMITTER_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>HepaRG_LOngReads</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Other"/>
      <STUDY_ABSTRACT>To study DNA methylation (5mC and 5hmC) patterns associated with liver stemness, we profiled the HepaRG cell line at two stages of differentiation (i.e. proliferative and differentiated) and after selection of a side population with capacity to growth as spheres.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>Single molecule DNA methylation in a putative human liver progenitor cell line</CENTER_PROJECT_NAME>
      <STUDY_DESCRIPTION>To study DNA methylation (5mC and 5hmC) patterns associated with liver stemness, we profiled the HepaRG cell line at two stages of differentiation (i.e. proliferative and differentiated) and after selection of a side population with capacity to growth as spheres.</STUDY_DESCRIPTION>
    </DESCRIPTOR>
    <STUDY_ATTRIBUTES>
      <STUDY_ATTRIBUTE>
        <TAG>ENA-FIRST-PUBLIC</TAG>
        <VALUE>2023-02-01</VALUE>
      </STUDY_ATTRIBUTE>
      <STUDY_ATTRIBUTE>
        <TAG>ENA-LAST-UPDATE</TAG>
        <VALUE>2023-02-01</VALUE>
      </STUDY_ATTRIBUTE>
    </STUDY_ATTRIBUTES>
  </STUDY>
</STUDY_SET>
