ERP115598 PRJEB32866 E-MTAB-8016 RNA-seq of liver samples from adult Ryukyu mice (Mus caroli) We explored the relationship between the evolutionary dynamics of CTCF binding and the functional stability of higher order genome structures, by performing ChIP-seq experiments in closely related Mus species or strains and intersecting with Hi-C-derived topologically associating domains (TADs) and expression data. To complement our data analyses, we generated RNA-seq libraries from two Mus caroli adult male individuals. We explored the relationship between the evolutionary dynamics of CTCF binding and the functional stability of higher order genome structures, by performing ChIP-seq experiments in closely related Mus species or strains and intersecting with Hi-C-derived topologically associating domains (TADs) and expression data. To complement our data analyses, we generated RNA-seq libraries from two Mus caroli adult male individuals. E-MTAB-8016 in ArrayExpress http://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-8016 ENA-FIRST-PUBLIC 2019-11-20 ENA-LAST-UPDATE 2019-06-03