ERP118222 PRJEB35204 ena-STUDY-Charite Universitaetsmedizin-04-11-2019-11:09:18:379-16 Transcriptome analysis of murine Hdac2 knockout pancreatic tumor cells. We performed a knockout of Hdac2 in a dual recombinase system based and KrasG12D/+ driven mouse model of pancreatic ductal adenocarcinoma (n=3 biological; n= 2 technical replicates).Tamoxifen (4-OHT) treatment for 8 days excised the floxed Hdac2 alleles by the CreERT2 fusion protein. Ethanol (EtOH) served as a vehicle control. Genotype: FSF-KrasG12D/+, FSF-Trp53del/+, Pdx1-Flp, R26CAG-FSF-CreERT2/+, Pdk1loxP/+, Hdac2loxP/loxP HDAC in PDAC We performed a knockout of Hdac2 in a dual recombinase system based and KrasG12D/+ driven mouse model of pancreatic ductal adenocarcinoma (n=3 biological; n= 2 technical replicates).Tamoxifen (4-OHT) treatment for 8 days excised the floxed Hdac2 alleles by the CreERT2 fusion protein. Ethanol (EtOH) served as a vehicle control. Genotype: FSF-KrasG12D/+, FSF-Trp53del/+, Pdx1-Flp, R26CAG-FSF-CreERT2/+, Pdk1loxP/+, Hdac2loxP/loxP ENA-FIRST-PUBLIC 2020-02-19 ENA-LAST-UPDATE 2021-09-01