<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY accession="ERP149758" alias="E-MTAB-13200" broker_name="ArrayExpress" center_name="University of Ulm">
    <IDENTIFIERS>
      <PRIMARY_ID>ERP149758</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject">PRJEB64573</EXTERNAL_ID>
      <SUBMITTER_ID namespace="University of Ulm">E-MTAB-13200</SUBMITTER_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Transcriptional profiling of primary human peripheral blood monocytes isolated from neurologically unaffected controls and treated in culture with LPS or vehicle.</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Other"/>
      <STUDY_ABSTRACT>Inflammatory stimulation with lipopolysachharide (LPS) iduces a strong re-organization in the transcriptional program of human monocytes. We isolated peripheral blood monocytes from neurologically unaffected controls (n=8) and stimulated the monocytes in culture with LPS (1 ng/mL for 4 h) to investigate changes in gene expression upon LPS stimulation.</STUDY_ABSTRACT>
      <STUDY_DESCRIPTION>Inflammatory stimulation with lipopolysachharide (LPS) iduces a strong re-organization in the transcriptional program of human monocytes. We isolated peripheral blood monocytes from neurologically unaffected controls (n=8) and stimulated the monocytes in culture with LPS (1 ng/mL for 4 h) to investigate changes in gene expression upon LPS stimulation.</STUDY_DESCRIPTION>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <URL_LINK>
          <LABEL>E-MTAB-13200 in ArrayExpress</LABEL>
          <URL>https://www.ebi.ac.uk/biostudies/arrayexpress/studies/E-MTAB-13200</URL>
        </URL_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
    <STUDY_ATTRIBUTES>
      <STUDY_ATTRIBUTE>
        <TAG>ENA-FIRST-PUBLIC</TAG>
        <VALUE>2023-07-25</VALUE>
      </STUDY_ATTRIBUTE>
      <STUDY_ATTRIBUTE>
        <TAG>ENA-LAST-UPDATE</TAG>
        <VALUE>2023-07-25</VALUE>
      </STUDY_ATTRIBUTE>
    </STUDY_ATTRIBUTES>
  </STUDY>
</STUDY_SET>
