<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY accession="ERP123517" alias="European_wide_survey_of_carbapenem__and_or_colistin_resistant_Enterobacteriaceae-sc-6259" center_name="Wellcome Sanger Institute">
    <IDENTIFIERS>
      <PRIMARY_ID>ERP123517</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject">PRJEB39943</EXTERNAL_ID>
      <SUBMITTER_ID namespace="Wellcome Sanger Institute">European_wide_survey_of_carbapenem__and_or_colistin_resistant_Enterobacteriaceae-sc-6259</SUBMITTER_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>European_wide_survey_of_carbapenem__and_or_colistin_resistant_Enterobacteriaceae</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Whole Genome Sequencing"/>
      <STUDY_ABSTRACT>This study will use whole genome sequencing (WGS) data from Klebsiella pneumoniae and Escherichia coli isolates collected during the 2019 European-wide survey of carbapenem- and/or colistin-resistant Enterobacteriaceae. Isolates were collected from hospitals and their associated clinical microbiology laboratories in 37 countries during a six-month period. Both resistant and comparator susceptible isolates were collected. The WGS data will be used to analyse the population structure, with particular emphasis on the identification of high-risk clones. It will also be used to determine the prevalence, distribution and transmission dynamics of key resistance and virulence markers.</STUDY_ABSTRACT>
      <STUDY_DESCRIPTION>This study will use whole genome sequencing (WGS) data from Klebsiella pneumoniae and Escherichia coli isolates collected during the 2019 European-wide survey of carbapenem- and/or colistin-resistant Enterobacteriaceae. Isolates were collected from hospitals and their associated clinical microbiology laboratories in 37 countries during a six-month period. Both resistant and comparator susceptible isolates were collected. The WGS data will be used to analyse the population structure, with particular emphasis on the identification of high-risk clones. It will also be used to determine the prevalence, distribution and transmission dynamics of key resistance and virulence markers.  This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/</STUDY_DESCRIPTION>
    </DESCRIPTOR>
    <STUDY_ATTRIBUTES>
      <STUDY_ATTRIBUTE>
        <TAG>ENA-FIRST-PUBLIC</TAG>
        <VALUE>2021-12-15</VALUE>
      </STUDY_ATTRIBUTE>
      <STUDY_ATTRIBUTE>
        <TAG>ENA-LAST-UPDATE</TAG>
        <VALUE>2021-12-15</VALUE>
      </STUDY_ATTRIBUTE>
    </STUDY_ATTRIBUTES>
  </STUDY>
</STUDY_SET>
