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  <STUDY xmlns:com="SRA.common" alias="E-MTAB-4572" broker_name="ArrayExpress" accession="ERP014609" center_name="Center of Biomedical Research (CIBM) University of Granada">
    <IDENTIFIERS>
      <PRIMARY_ID>ERP014609</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject">PRJEB13073</EXTERNAL_ID>
      <SUBMITTER_ID namespace="Center of Biomedical Research (CIBM) University of Granada">E-MTAB-4572</SUBMITTER_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Testis-to-ovary reprogramming and testis regression after ablation of Sox9 in Sox8-/- mice</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>We used two Sertoli-cell-specific Cre lines: Wt1-CreERT2 and Sox9-CreERT2, to induce Sox9 ablation on a Sox8 -/- background in the adult testis. Sox9/8 double KO testes undergo testis-to-ovary genetic reprogramming and Sertoli-to-granulosa cell transdifferentiation.</STUDY_ABSTRACT>
      <STUDY_DESCRIPTION>We used two Sertoli-cell-specific Cre lines: Wt1-CreERT2 and Sox9-CreERT2, to induce Sox9 ablation on a Sox8 -/- background in the adult testis. Sox9/8 double KO testes undergo testis-to-ovary genetic reprogramming and Sertoli-to-granulosa cell transdifferentiation.</STUDY_DESCRIPTION>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <URL_LINK>
          <LABEL>E-MTAB-4572 in ArrayExpress</LABEL>
          <URL>http://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-4572</URL>
        </URL_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
    <STUDY_ATTRIBUTES>
      <STUDY_ATTRIBUTE>
        <TAG>ArrayExpress</TAG>
        <VALUE>E-MTAB-4572</VALUE>
      </STUDY_ATTRIBUTE>
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  </STUDY>
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