ERP015528 PRJEB13941 ena-STUDY-FISABIO - Public Health-10-05-2016-11:30:30:172-255 Temporal stability of the salivary microbiome and its association with salivary markers of oxidative stress Salivary markers of oxidative stress are associated with periodontal status and are altered in patients with periodontitis or caries. It has been hypothesized that the composition of oral microbiome and the presence of specific bacterial species might be associated with some salivary markers of oxidative stress. The day to day variability of salivary markers of oxidative stress has been described. More detailed studies are needed for the assessment of salivary microbiome stability. The objective of the present study is to study temporal stability of saliva microbiome and to analyze its association to variations of salivary markers of oxidative stress. Salivary markers of oxidative stress are associated with periodontal status and are altered in patients with periodontitis or caries. It has been hypothesized that the composition of oral microbiome and the presence of specific bacterial species might be associated with some salivary markers of oxidative stress. The day to day variability of salivary markers of oxidative stress has been described. More detailed studies are needed for the assessment of salivary microbiome stability. The objective of the present study is to study temporal stability of saliva microbiome and to analyze its association to variations of salivary markers of oxidative stress.