ERP132462 PRJEB48141 E-MTAB-11053 RNA-seq of human HT-29 WT and SMYD2-KO xenograft implanted into the flanks of Rag1-/- mice Our data suggested that SMYD2 deficiency sensitized cells to apoptosis and necroptosis.To further narrow down the mechanism of cell death induction upon SMYD2 deficiency, RNA-seq analysis was performed on implanted tumor tissues from two clones of SMYD2 deficient and WT HT-29 cells. Our data suggested that SMYD2 deficiency sensitized cells to apoptosis and necroptosis.To further narrow down the mechanism of cell death induction upon SMYD2 deficiency, RNA-seq analysis was performed on implanted tumor tissues from two clones of SMYD2 deficient and WT HT-29 cells. E-MTAB-11053 in ArrayExpress http://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-11053 ENA-FIRST-PUBLIC 2021-10-18 ENA-LAST-UPDATE 2021-10-18