SRX272860 GSM1131186_1 SRP021911 GSE46489 SRS417369 GSM1131186 RNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was extracted using the miRNeasy Mini Kit (Qiagen), according to the manufacturer’s instructions. Small RNA fraction (< 200nt) was eluted separately from large RNA fraction. Small RNA libraries were prepared using Bioo Scientific NEXTflex Small RNA Sequencing Kit and NEXTflex small RNA Barcode Primer Set A (Bioo Scientific Corporation) following the manufacturer’s protocol. Size selection of 140-160 bp fragments corresponding to mature miRNAs and adapters was carried out by gel electrophoresis with 10% Mini-PROTEAN TBE Precast gels (Bio-Rad Laboratories). 0.66 pM of individual indexed samples were pooled for template hybridization and clustering/amplification was performed using TruSeq SR Cluster Kit v2-cBot-GA (Illumina). Illumina Genome Analyzer IIx GEO Sample http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1131186 gds 301131186 GEO Accession GSM1131186 SRX272861 GSM1131187_1 SRP021911 GSE46489 SRS417370 GSM1131187 RNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was extracted using the miRNeasy Mini Kit (Qiagen), according to the manufacturer’s instructions. Small RNA fraction (< 200nt) was eluted separately from large RNA fraction. Small RNA libraries were prepared using Bioo Scientific NEXTflex Small RNA Sequencing Kit and NEXTflex small RNA Barcode Primer Set A (Bioo Scientific Corporation) following the manufacturer’s protocol. Size selection of 140-160 bp fragments corresponding to mature miRNAs and adapters was carried out by gel electrophoresis with 10% Mini-PROTEAN TBE Precast gels (Bio-Rad Laboratories). 0.66 pM of individual indexed samples were pooled for template hybridization and clustering/amplification was performed using TruSeq SR Cluster Kit v2-cBot-GA (Illumina). Illumina Genome Analyzer IIx GEO Sample http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1131187 gds 301131187 GEO Accession GSM1131187 SRX272862 GSM1131188_1 SRP021911 GSE46489 SRS417371 GSM1131188 RNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was extracted using the miRNeasy Mini Kit (Qiagen), according to the manufacturer’s instructions. Small RNA fraction (< 200nt) was eluted separately from large RNA fraction. Small RNA libraries were prepared using Bioo Scientific NEXTflex Small RNA Sequencing Kit and NEXTflex small RNA Barcode Primer Set A (Bioo Scientific Corporation) following the manufacturer’s protocol. Size selection of 140-160 bp fragments corresponding to mature miRNAs and adapters was carried out by gel electrophoresis with 10% Mini-PROTEAN TBE Precast gels (Bio-Rad Laboratories). 0.66 pM of individual indexed samples were pooled for template hybridization and clustering/amplification was performed using TruSeq SR Cluster Kit v2-cBot-GA (Illumina). Illumina Genome Analyzer IIx GEO Sample http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1131188 gds 301131188 GEO Accession GSM1131188 SRX272863 GSM1131189_1 SRP021911 GSE46489 SRS417372 GSM1131189 RNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was extracted using the miRNeasy Mini Kit (Qiagen), according to the manufacturer’s instructions. Small RNA fraction (< 200nt) was eluted separately from large RNA fraction. Small RNA libraries were prepared using Bioo Scientific NEXTflex Small RNA Sequencing Kit and NEXTflex small RNA Barcode Primer Set A (Bioo Scientific Corporation) following the manufacturer’s protocol. Size selection of 140-160 bp fragments corresponding to mature miRNAs and adapters was carried out by gel electrophoresis with 10% Mini-PROTEAN TBE Precast gels (Bio-Rad Laboratories). 0.66 pM of individual indexed samples were pooled for template hybridization and clustering/amplification was performed using TruSeq SR Cluster Kit v2-cBot-GA (Illumina). Illumina Genome Analyzer IIx GEO Sample http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1131189 gds 301131189 GEO Accession GSM1131189 SRX272864 GSM1131190_1 SRP021911 GSE46489 SRS417373 GSM1131190 RNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was extracted using the miRNeasy Mini Kit (Qiagen), according to the manufacturer’s instructions. Small RNA fraction (< 200nt) was eluted separately from large RNA fraction. Small RNA libraries were prepared using Bioo Scientific NEXTflex Small RNA Sequencing Kit and NEXTflex small RNA Barcode Primer Set A (Bioo Scientific Corporation) following the manufacturer’s protocol. Size selection of 140-160 bp fragments corresponding to mature miRNAs and adapters was carried out by gel electrophoresis with 10% Mini-PROTEAN TBE Precast gels (Bio-Rad Laboratories). 0.66 pM of individual indexed samples were pooled for template hybridization and clustering/amplification was performed using TruSeq SR Cluster Kit v2-cBot-GA (Illumina). Illumina Genome Analyzer IIx GEO Sample http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1131190 gds 301131190 GEO Accession GSM1131190 SRX272865 GSM1131191_1 SRP021911 GSE46489 SRS417374 GSM1131191 RNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was extracted using the miRNeasy Mini Kit (Qiagen), according to the manufacturer’s instructions. Small RNA fraction (< 200nt) was eluted separately from large RNA fraction. Small RNA libraries were prepared using Bioo Scientific NEXTflex Small RNA Sequencing Kit and NEXTflex small RNA Barcode Primer Set A (Bioo Scientific Corporation) following the manufacturer’s protocol. Size selection of 140-160 bp fragments corresponding to mature miRNAs and adapters was carried out by gel electrophoresis with 10% Mini-PROTEAN TBE Precast gels (Bio-Rad Laboratories). 0.66 pM of individual indexed samples were pooled for template hybridization and clustering/amplification was performed using TruSeq SR Cluster Kit v2-cBot-GA (Illumina). Illumina Genome Analyzer IIx GEO Sample http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1131191 gds 301131191 GEO Accession GSM1131191