SRX7237246 A1 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723428 SAMN11811752 A1 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237247 A2 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723429 SAMN11811753 A2 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237248 A11 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723430 SAMN11811762 A11 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237249 B28 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723479 SAMN11811807 B28 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237250 A7 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723480 SAMN11811758 A7 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237251 A8 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723481 SAMN11811759 A8 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237252 A9 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723482 SAMN11811760 A9 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237253 A10 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723483 SAMN11811761 A10 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237254 A12 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723431 SAMN11811763 A12 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237255 A13 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723432 SAMN11811764 A13 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237256 A14 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723433 SAMN11811765 A14 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237257 A15 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723434 SAMN11811766 A15 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237258 A16 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723435 SAMN11811767 A16 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237259 A17 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723436 SAMN11811768 A17 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237260 A18 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723437 SAMN11811769 A18 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237261 A19 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723438 SAMN11811770 A19 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237262 A20 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723439 SAMN11811771 A20 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237263 A3 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723440 SAMN11811754 A3 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237264 A21 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723441 SAMN11811772 A21 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237265 A22 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723442 SAMN11811773 A22 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237266 A23 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723443 SAMN11811774 A23 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237267 A24 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723444 SAMN11811775 A24 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237268 A25 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723445 SAMN11811776 A25 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237269 A26 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723446 SAMN11811777 A26 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237270 A27 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723447 SAMN11811778 A27 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237271 A28 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723448 SAMN11811779 A28 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237272 B1 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723449 SAMN11811780 B1 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237273 B2 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723450 SAMN11811781 B2 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237274 A4 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723451 SAMN11811755 A4 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237275 B3 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723452 SAMN11811782 B3 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237276 B4 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723453 SAMN11811783 B4 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237277 B5 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723454 SAMN11811784 B5 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237278 B6 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723455 SAMN11811785 B6 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237279 B7 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723456 SAMN11811786 B7 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237280 B8 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723457 SAMN11811787 B8 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237281 B9 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723458 SAMN11811788 B9 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237282 B10 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723459 SAMN11811789 B10 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237283 B11 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723460 SAMN11811790 B11 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237284 B12 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723461 SAMN11811791 B12 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237285 A5 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723462 SAMN11811756 A5 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237286 B13 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723463 SAMN11811792 B13 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237287 B14 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723464 SAMN11811793 B14 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237288 B15 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723465 SAMN11811794 B15 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237289 B16 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723466 SAMN11811795 B16 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237290 B17 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723467 SAMN11811796 B17 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237291 B18 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723468 SAMN11811797 B18 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237292 B19 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723469 SAMN11811798 B19 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237293 B20 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723470 SAMN11811799 B20 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237294 B21 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723471 SAMN11811800 B21 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237295 B22 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723472 SAMN11811801 B22 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237296 A6 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723473 SAMN11811757 A6 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237297 B23 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723474 SAMN11811802 B23 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237298 B24 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723475 SAMN11811803 B24 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237299 B25 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723476 SAMN11811804 B25 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237300 B26 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723477 SAMN11811805 B26 WXS METAGENOMIC PCR Illumina HiSeq 2500 SRX7237301 B27 SRP233345 PRJNA544346 Stool microbial genomic DNA was extracted from human fecal sample, V3-V4 region of bacteria 16S rRNA was amplified from the isolated microbial genomic DNA. The nucleotide sequence of the primer was 341F: 5'-CCT AYG GGR BGC ASA CG-3', 806R: 5'-GGA CTA CNN GGG TAT CTA AT-3'. PCR fragments with desired size (approximately 465bp) was purified, DNA quality and concentration was checked. Each sample had 3 replications. The purified fragments of each sample were normalized and pooled. Pyrosequencing of the samples was sequenced using Illumina Hiseq 2500. SRS5723478 SAMN11811806 B27 WXS METAGENOMIC PCR Illumina HiSeq 2500