SRX7266853 GSM4202655 GSM4202655: Saline self-administration Rep1 [64]; Mus musculus; RNA-Seq SRP234690 SRS5761443 GSM4202655 RNA-Seq TRANSCRIPTOMIC cDNA The whole striatum was dissected and homogenized and tagged polysomes were immunopurified with monoclonal anti-EGFP antibodies bound to biotinylated-Protein L (Thermo Fisher) coated streptavidin-conjugated magnetic beads (Life Technologies). Total RNA from IPs was purified with the Agilent Nanoprep kit following manufacturer's protocol. Ribosomal-bound RNA was extracted and treated as described in PMID 24810037, Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N. (2014) Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP). Nat Protoc. 9:1282-1291 Illumina HiSeq 2500 gds 304202655 GEO Accession GSM4202655 SRX7266855 GSM4202656 GSM4202656: Cocaine self-administration Rep1 [65]; Mus musculus; RNA-Seq SRP234690 SRS5761446 GSM4202656 RNA-Seq TRANSCRIPTOMIC cDNA The whole striatum was dissected and homogenized and tagged polysomes were immunopurified with monoclonal anti-EGFP antibodies bound to biotinylated-Protein L (Thermo Fisher) coated streptavidin-conjugated magnetic beads (Life Technologies). Total RNA from IPs was purified with the Agilent Nanoprep kit following manufacturer's protocol. Ribosomal-bound RNA was extracted and treated as described in PMID 24810037, Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N. (2014) Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP). Nat Protoc. 9:1282-1291 Illumina HiSeq 2500 gds 304202656 GEO Accession GSM4202656 SRX7266857 GSM4202657 GSM4202657: Yoked control Rep1 [66]; Mus musculus; RNA-Seq SRP234690 SRS5761445 GSM4202657 RNA-Seq TRANSCRIPTOMIC cDNA The whole striatum was dissected and homogenized and tagged polysomes were immunopurified with monoclonal anti-EGFP antibodies bound to biotinylated-Protein L (Thermo Fisher) coated streptavidin-conjugated magnetic beads (Life Technologies). Total RNA from IPs was purified with the Agilent Nanoprep kit following manufacturer's protocol. Ribosomal-bound RNA was extracted and treated as described in PMID 24810037, Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N. (2014) Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP). Nat Protoc. 9:1282-1291 Illumina HiSeq 2500 gds 304202657 GEO Accession GSM4202657 SRX7266859 GSM4202658 GSM4202658: Saline self-administration Rep2 [67]; Mus musculus; RNA-Seq SRP234690 SRS5761448 GSM4202658 RNA-Seq TRANSCRIPTOMIC cDNA The whole striatum was dissected and homogenized and tagged polysomes were immunopurified with monoclonal anti-EGFP antibodies bound to biotinylated-Protein L (Thermo Fisher) coated streptavidin-conjugated magnetic beads (Life Technologies). Total RNA from IPs was purified with the Agilent Nanoprep kit following manufacturer's protocol. Ribosomal-bound RNA was extracted and treated as described in PMID 24810037, Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N. (2014) Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP). Nat Protoc. 9:1282-1291 Illumina HiSeq 2500 gds 304202658 GEO Accession GSM4202658 SRX7266861 GSM4202659 GSM4202659: Cocaine self-administration Rep2 [68]; Mus musculus; RNA-Seq SRP234690 SRS5761450 GSM4202659 RNA-Seq TRANSCRIPTOMIC cDNA The whole striatum was dissected and homogenized and tagged polysomes were immunopurified with monoclonal anti-EGFP antibodies bound to biotinylated-Protein L (Thermo Fisher) coated streptavidin-conjugated magnetic beads (Life Technologies). Total RNA from IPs was purified with the Agilent Nanoprep kit following manufacturer's protocol. Ribosomal-bound RNA was extracted and treated as described in PMID 24810037, Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N. (2014) Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP). Nat Protoc. 9:1282-1291 Illumina HiSeq 2500 gds 304202659 GEO Accession GSM4202659 SRX7266863 GSM4202660 GSM4202660: Yoked control Rep2 [69]; Mus musculus; RNA-Seq SRP234690 SRS5761452 GSM4202660 RNA-Seq TRANSCRIPTOMIC cDNA The whole striatum was dissected and homogenized and tagged polysomes were immunopurified with monoclonal anti-EGFP antibodies bound to biotinylated-Protein L (Thermo Fisher) coated streptavidin-conjugated magnetic beads (Life Technologies). Total RNA from IPs was purified with the Agilent Nanoprep kit following manufacturer's protocol. Ribosomal-bound RNA was extracted and treated as described in PMID 24810037, Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N. (2014) Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP). Nat Protoc. 9:1282-1291 Illumina HiSeq 2500 gds 304202660 GEO Accession GSM4202660 SRX7266865 GSM4202661 GSM4202661: Saline self-administration Rep3 [70]; Mus musculus; RNA-Seq SRP234690 SRS5761454 GSM4202661 RNA-Seq TRANSCRIPTOMIC cDNA The whole striatum was dissected and homogenized and tagged polysomes were immunopurified with monoclonal anti-EGFP antibodies bound to biotinylated-Protein L (Thermo Fisher) coated streptavidin-conjugated magnetic beads (Life Technologies). Total RNA from IPs was purified with the Agilent Nanoprep kit following manufacturer's protocol. Ribosomal-bound RNA was extracted and treated as described in PMID 24810037, Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N. (2014) Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP). Nat Protoc. 9:1282-1291 Illumina HiSeq 2500 gds 304202661 GEO Accession GSM4202661 SRX7266867 GSM4202662 GSM4202662: Cocaine self-administration Rep3 [71]; Mus musculus; RNA-Seq SRP234690 SRS5761456 GSM4202662 RNA-Seq TRANSCRIPTOMIC cDNA The whole striatum was dissected and homogenized and tagged polysomes were immunopurified with monoclonal anti-EGFP antibodies bound to biotinylated-Protein L (Thermo Fisher) coated streptavidin-conjugated magnetic beads (Life Technologies). Total RNA from IPs was purified with the Agilent Nanoprep kit following manufacturer's protocol. Ribosomal-bound RNA was extracted and treated as described in PMID 24810037, Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N. (2014) Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP). Nat Protoc. 9:1282-1291 Illumina HiSeq 2500 gds 304202662 GEO Accession GSM4202662 SRX7266869 GSM4202663 GSM4202663: Yoked control Rep3 [72]; Mus musculus; RNA-Seq SRP234690 SRS5761457 GSM4202663 RNA-Seq TRANSCRIPTOMIC cDNA The whole striatum was dissected and homogenized and tagged polysomes were immunopurified with monoclonal anti-EGFP antibodies bound to biotinylated-Protein L (Thermo Fisher) coated streptavidin-conjugated magnetic beads (Life Technologies). Total RNA from IPs was purified with the Agilent Nanoprep kit following manufacturer's protocol. Ribosomal-bound RNA was extracted and treated as described in PMID 24810037, Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N. (2014) Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP). Nat Protoc. 9:1282-1291 Illumina HiSeq 2500 gds 304202663 GEO Accession GSM4202663 SRX7266871 GSM4202664 GSM4202664: Input [73]; Mus musculus; RNA-Seq SRP234690 SRS5761458 GSM4202664 RNA-Seq TRANSCRIPTOMIC cDNA The whole striatum was dissected and homogenized and tagged polysomes were immunopurified with monoclonal anti-EGFP antibodies bound to biotinylated-Protein L (Thermo Fisher) coated streptavidin-conjugated magnetic beads (Life Technologies). Total RNA from IPs was purified with the Agilent Nanoprep kit following manufacturer's protocol. Ribosomal-bound RNA was extracted and treated as described in PMID 24810037, Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N. (2014) Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP). Nat Protoc. 9:1282-1291 Illumina HiSeq 2500 gds 304202664 GEO Accession GSM4202664