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      <PRIMARY_ID>SRX381817</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Analysis of tandem repeat variability in a three-generation nuclear family</TITLE>
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        <PRIMARY_ID>SRP033260</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>Tandem repeats are short DNA sequences that are repeated head-to-tail with a propensity to be unstable. They constitute a significant proportion of the human genome, also occurring within coding and regulatory regions. Variation in these repeats can alter the function and/or expression of genes allowing organisms to swiftly adapt to novel environments.  On the other hand, some repeat expansions have also been linked to certain neurodegenerative diseases. Therefore, accurate sequencing of tandem repeats could contribute to our understanding of common phenotypic variability and might uncover missing genetic factors in idiopathic clinical conditions. Therefore, we simultaneous sequenced thousands of tandem repeats in the human genomes of a three generation family using GS-FLX-plus Titanium technology.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS506035</PRIMARY_ID>
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      <PRIMARY_ID>SRX381818</PRIMARY_ID>
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    <TITLE>Analysis of tandem repeat variability in a three-generation nuclear family</TITLE>
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        <PRIMARY_ID>SRP033260</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>Tandem repeats are short DNA sequences that are repeated head-to-tail with a propensity to be unstable. They constitute a significant proportion of the human genome, also occurring within coding and regulatory regions. Variation in these repeats can alter the function and/or expression of genes allowing organisms to swiftly adapt to novel environments.  On the other hand, some repeat expansions have also been linked to certain neurodegenerative diseases. Therefore, accurate sequencing of tandem repeats could contribute to our understanding of common phenotypic variability and might uncover missing genetic factors in idiopathic clinical conditions. Therefore, we simultaneous sequenced thousands of tandem repeats in the human genomes of a three generation family using GS-FLX-plus Titanium technology.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS506036</PRIMARY_ID>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX381819</PRIMARY_ID>
      <SUBMITTER_ID namespace="CME">family repeat 454: father</SUBMITTER_ID>
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    <TITLE>Analysis of tandem repeat variability in a three-generation nuclear family</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>Tandem repeats are short DNA sequences that are repeated head-to-tail with a propensity to be unstable. They constitute a significant proportion of the human genome, also occurring within coding and regulatory regions. Variation in these repeats can alter the function and/or expression of genes allowing organisms to swiftly adapt to novel environments.  On the other hand, some repeat expansions have also been linked to certain neurodegenerative diseases. Therefore, accurate sequencing of tandem repeats could contribute to our understanding of common phenotypic variability and might uncover missing genetic factors in idiopathic clinical conditions. Therefore, we simultaneous sequenced thousands of tandem repeats in the human genomes of a three generation family using GS-FLX-plus Titanium technology.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS506037</PRIMARY_ID>
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        <LIBRARY_NAME>Rapid library prep, shotgun GS-FLX</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>454 GS FLX+</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX381820</PRIMARY_ID>
      <SUBMITTER_ID namespace="CME">family repeat 454: grandmother</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Analysis of tandem repeat variability in a three-generation nuclear family</TITLE>
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        <PRIMARY_ID>SRP033260</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>Tandem repeats are short DNA sequences that are repeated head-to-tail with a propensity to be unstable. They constitute a significant proportion of the human genome, also occurring within coding and regulatory regions. Variation in these repeats can alter the function and/or expression of genes allowing organisms to swiftly adapt to novel environments.  On the other hand, some repeat expansions have also been linked to certain neurodegenerative diseases. Therefore, accurate sequencing of tandem repeats could contribute to our understanding of common phenotypic variability and might uncover missing genetic factors in idiopathic clinical conditions. Therefore, we simultaneous sequenced thousands of tandem repeats in the human genomes of a three generation family using GS-FLX-plus Titanium technology.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS506038</PRIMARY_ID>
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        <LIBRARY_NAME>Rapid library prep, shotgun GS-FLX</LIBRARY_NAME>
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      <PRIMARY_ID>SRX381821</PRIMARY_ID>
      <SUBMITTER_ID namespace="CME">family repeat 454: grandfather</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Analysis of tandem repeat variability in a three-generation nuclear family</TITLE>
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        <PRIMARY_ID>SRP033260</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>Tandem repeats are short DNA sequences that are repeated head-to-tail with a propensity to be unstable. They constitute a significant proportion of the human genome, also occurring within coding and regulatory regions. Variation in these repeats can alter the function and/or expression of genes allowing organisms to swiftly adapt to novel environments.  On the other hand, some repeat expansions have also been linked to certain neurodegenerative diseases. Therefore, accurate sequencing of tandem repeats could contribute to our understanding of common phenotypic variability and might uncover missing genetic factors in idiopathic clinical conditions. Therefore, we simultaneous sequenced thousands of tandem repeats in the human genomes of a three generation family using GS-FLX-plus Titanium technology.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS506039</PRIMARY_ID>
          <EXTERNAL_ID namespace="BioSample">SAMN02418761</EXTERNAL_ID>
        </IDENTIFIERS>
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        <LIBRARY_NAME>Rapid library prep, shotgun GS-FLX</LIBRARY_NAME>
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  <EXPERIMENT alias="family repeat 454: kid1" accession="SRX381822" center_name="CME">
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      <PRIMARY_ID>SRX381822</PRIMARY_ID>
      <SUBMITTER_ID namespace="CME">family repeat 454: kid1</SUBMITTER_ID>
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    <TITLE>Analysis of tandem repeat variability in a three-generation nuclear family</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP033260</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>Tandem repeats are short DNA sequences that are repeated head-to-tail with a propensity to be unstable. They constitute a significant proportion of the human genome, also occurring within coding and regulatory regions. Variation in these repeats can alter the function and/or expression of genes allowing organisms to swiftly adapt to novel environments.  On the other hand, some repeat expansions have also been linked to certain neurodegenerative diseases. Therefore, accurate sequencing of tandem repeats could contribute to our understanding of common phenotypic variability and might uncover missing genetic factors in idiopathic clinical conditions. Therefore, we simultaneous sequenced thousands of tandem repeats in the human genomes of a three generation family using GS-FLX-plus Titanium technology.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS506040</PRIMARY_ID>
          <EXTERNAL_ID namespace="BioSample">SAMN02418763</EXTERNAL_ID>
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        <LIBRARY_NAME>Rapid library prep, shotgun GS-FLX</LIBRARY_NAME>
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      <PRIMARY_ID>SRX381823</PRIMARY_ID>
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    <TITLE>Analysis of tandem repeat variability in a three-generation nuclear family</TITLE>
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        <PRIMARY_ID>SRP033260</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>Tandem repeats are short DNA sequences that are repeated head-to-tail with a propensity to be unstable. They constitute a significant proportion of the human genome, also occurring within coding and regulatory regions. Variation in these repeats can alter the function and/or expression of genes allowing organisms to swiftly adapt to novel environments.  On the other hand, some repeat expansions have also been linked to certain neurodegenerative diseases. Therefore, accurate sequencing of tandem repeats could contribute to our understanding of common phenotypic variability and might uncover missing genetic factors in idiopathic clinical conditions. Therefore, we simultaneous sequenced thousands of tandem repeats in the human genomes of a three generation family using GS-FLX-plus Titanium technology.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX381824</PRIMARY_ID>
      <SUBMITTER_ID namespace="CME">family repeat 454: kid3</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Analysis of tandem repeat variability in a three-generation nuclear family</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP033260</PRIMARY_ID>
        <EXTERNAL_ID namespace="BioProject">PRJNA229524</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>Tandem repeats are short DNA sequences that are repeated head-to-tail with a propensity to be unstable. They constitute a significant proportion of the human genome, also occurring within coding and regulatory regions. Variation in these repeats can alter the function and/or expression of genes allowing organisms to swiftly adapt to novel environments.  On the other hand, some repeat expansions have also been linked to certain neurodegenerative diseases. Therefore, accurate sequencing of tandem repeats could contribute to our understanding of common phenotypic variability and might uncover missing genetic factors in idiopathic clinical conditions. Therefore, we simultaneous sequenced thousands of tandem repeats in the human genomes of a three generation family using GS-FLX-plus Titanium technology.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS506042</PRIMARY_ID>
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        <LIBRARY_NAME>Rapid library prep, shotgun GS-FLX</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>454 GS FLX+</INSTRUMENT_MODEL>
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