<?xml version="1.0" encoding="UTF-8"?>
<EXPERIMENT_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <EXPERIMENT alias="GSM1272357" accession="SRX381110" center_name="GEO">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX381110</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM1272357</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM1272357: H1A T0 input; Homo sapiens; OTHER</TITLE>
    <STUDY_REF accession="SRP033229" refname="GSE52600">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP033229</PRIMARY_ID>
        <SUBMITTER_ID namespace="GEO">GSE52600</SUBMITTER_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS505504">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS505504</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM1272357</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>OTHER</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <SINGLE/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Cells well harvested by direct addition of TRIzol reagent (Ambion Cat.#15596018) to the cell culture plate after removal of the media and extracted using Trizol reagent protocol. Subsequently, the total RNA was DNase treated using DNase I (Promega Cat.# M610A) for 20 minutes at 37ºC followed by acid phenol/chloroform extraction, chloroform extraction and overnight NaCl2 precipitation. The precipitated RNA was washed with 70ºC ethanol and re-suspended in ultra pure H2O. RNA concentration and purity were verified by nanodrop followed by BioAnalyzer for quality control. Double polyA+ RNA selection was performed using twice Invitrogen Dynabeads mRNA Purification Kit (Cat. #610.06) protocol. RNA concentration and purity were once again verified by nanodrop followed by BioAnalyzer for quality control. For the input and post m6A-RNA IP fraction (i.e. m6A positive fraction), 100ng of RNA was used for library construction using TrueSeq Stranded mRNA Sample Preparation Guide, entering the protocol by adding the Fragment, Prime, Finish Mix, skipping the elution step and proceeding directly to synthesis of the First Strand cDNA. From that point on, the exact steps of the Illumina TruSeq Stranded mRNA sample Preparation Guide were followed to the end.</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <URL_LINK>
          <LABEL>GEO Sample GSM1272357</LABEL>
          <URL>http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1272357</URL>
        </URL_LINK>
      </EXPERIMENT_LINK>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>301272357</ID>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>GEO Accession</TAG>
        <VALUE>GSM1272357</VALUE>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM1272358" accession="SRX381111" center_name="GEO">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX381111</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM1272358</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM1272358: H1A T0 eluate; Homo sapiens; OTHER</TITLE>
    <STUDY_REF accession="SRP033229" refname="GSE52600">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP033229</PRIMARY_ID>
        <SUBMITTER_ID namespace="GEO">GSE52600</SUBMITTER_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS505503">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS505503</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM1272358</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>OTHER</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <SINGLE/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Cells well harvested by direct addition of TRIzol reagent (Ambion Cat.#15596018) to the cell culture plate after removal of the media and extracted using Trizol reagent protocol. Subsequently, the total RNA was DNase treated using DNase I (Promega Cat.# M610A) for 20 minutes at 37ºC followed by acid phenol/chloroform extraction, chloroform extraction and overnight NaCl2 precipitation. The precipitated RNA was washed with 70ºC ethanol and re-suspended in ultra pure H2O. RNA concentration and purity were verified by nanodrop followed by BioAnalyzer for quality control. Double polyA+ RNA selection was performed using twice Invitrogen Dynabeads mRNA Purification Kit (Cat. #610.06) protocol. RNA concentration and purity were once again verified by nanodrop followed by BioAnalyzer for quality control. For the input and post m6A-RNA IP fraction (i.e. m6A positive fraction), 100ng of RNA was used for library construction using TrueSeq Stranded mRNA Sample Preparation Guide, entering the protocol by adding the Fragment, Prime, Finish Mix, skipping the elution step and proceeding directly to synthesis of the First Strand cDNA. From that point on, the exact steps of the Illumina TruSeq Stranded mRNA sample Preparation Guide were followed to the end.</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <URL_LINK>
          <LABEL>GEO Sample GSM1272358</LABEL>
          <URL>http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1272358</URL>
        </URL_LINK>
      </EXPERIMENT_LINK>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>301272358</ID>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>GEO Accession</TAG>
        <VALUE>GSM1272358</VALUE>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM1272359" accession="SRX381112" center_name="GEO">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX381112</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM1272359</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM1272359: H1B T0 input; Homo sapiens; OTHER</TITLE>
    <STUDY_REF accession="SRP033229" refname="GSE52600">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP033229</PRIMARY_ID>
        <SUBMITTER_ID namespace="GEO">GSE52600</SUBMITTER_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS505505">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS505505</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM1272359</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>OTHER</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <SINGLE/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Cells well harvested by direct addition of TRIzol reagent (Ambion Cat.#15596018) to the cell culture plate after removal of the media and extracted using Trizol reagent protocol. Subsequently, the total RNA was DNase treated using DNase I (Promega Cat.# M610A) for 20 minutes at 37ºC followed by acid phenol/chloroform extraction, chloroform extraction and overnight NaCl2 precipitation. The precipitated RNA was washed with 70ºC ethanol and re-suspended in ultra pure H2O. RNA concentration and purity were verified by nanodrop followed by BioAnalyzer for quality control. Double polyA+ RNA selection was performed using twice Invitrogen Dynabeads mRNA Purification Kit (Cat. #610.06) protocol. RNA concentration and purity were once again verified by nanodrop followed by BioAnalyzer for quality control. For the input and post m6A-RNA IP fraction (i.e. m6A positive fraction), 100ng of RNA was used for library construction using TrueSeq Stranded mRNA Sample Preparation Guide, entering the protocol by adding the Fragment, Prime, Finish Mix, skipping the elution step and proceeding directly to synthesis of the First Strand cDNA. From that point on, the exact steps of the Illumina TruSeq Stranded mRNA sample Preparation Guide were followed to the end.</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <URL_LINK>
          <LABEL>GEO Sample GSM1272359</LABEL>
          <URL>http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1272359</URL>
        </URL_LINK>
      </EXPERIMENT_LINK>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>301272359</ID>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>GEO Accession</TAG>
        <VALUE>GSM1272359</VALUE>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM1272360" accession="SRX381113" center_name="GEO">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX381113</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM1272360</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM1272360: H1B T0 eluate; Homo sapiens; OTHER</TITLE>
    <STUDY_REF accession="SRP033229" refname="GSE52600">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP033229</PRIMARY_ID>
        <SUBMITTER_ID namespace="GEO">GSE52600</SUBMITTER_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS505506">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS505506</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM1272360</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>OTHER</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <SINGLE/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Cells well harvested by direct addition of TRIzol reagent (Ambion Cat.#15596018) to the cell culture plate after removal of the media and extracted using Trizol reagent protocol. Subsequently, the total RNA was DNase treated using DNase I (Promega Cat.# M610A) for 20 minutes at 37ºC followed by acid phenol/chloroform extraction, chloroform extraction and overnight NaCl2 precipitation. The precipitated RNA was washed with 70ºC ethanol and re-suspended in ultra pure H2O. RNA concentration and purity were verified by nanodrop followed by BioAnalyzer for quality control. Double polyA+ RNA selection was performed using twice Invitrogen Dynabeads mRNA Purification Kit (Cat. #610.06) protocol. RNA concentration and purity were once again verified by nanodrop followed by BioAnalyzer for quality control. For the input and post m6A-RNA IP fraction (i.e. m6A positive fraction), 100ng of RNA was used for library construction using TrueSeq Stranded mRNA Sample Preparation Guide, entering the protocol by adding the Fragment, Prime, Finish Mix, skipping the elution step and proceeding directly to synthesis of the First Strand cDNA. From that point on, the exact steps of the Illumina TruSeq Stranded mRNA sample Preparation Guide were followed to the end.</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <URL_LINK>
          <LABEL>GEO Sample GSM1272360</LABEL>
          <URL>http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1272360</URL>
        </URL_LINK>
      </EXPERIMENT_LINK>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>301272360</ID>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>GEO Accession</TAG>
        <VALUE>GSM1272360</VALUE>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM1272361" accession="SRX381114" center_name="GEO">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX381114</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM1272361</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM1272361: H1A T48 input; Homo sapiens; OTHER</TITLE>
    <STUDY_REF accession="SRP033229" refname="GSE52600">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP033229</PRIMARY_ID>
        <SUBMITTER_ID namespace="GEO">GSE52600</SUBMITTER_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS505507">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS505507</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM1272361</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>OTHER</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <SINGLE/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Cells well harvested by direct addition of TRIzol reagent (Ambion Cat.#15596018) to the cell culture plate after removal of the media and extracted using Trizol reagent protocol. Subsequently, the total RNA was DNase treated using DNase I (Promega Cat.# M610A) for 20 minutes at 37ºC followed by acid phenol/chloroform extraction, chloroform extraction and overnight NaCl2 precipitation. The precipitated RNA was washed with 70ºC ethanol and re-suspended in ultra pure H2O. RNA concentration and purity were verified by nanodrop followed by BioAnalyzer for quality control. Double polyA+ RNA selection was performed using twice Invitrogen Dynabeads mRNA Purification Kit (Cat. #610.06) protocol. RNA concentration and purity were once again verified by nanodrop followed by BioAnalyzer for quality control. For the input and post m6A-RNA IP fraction (i.e. m6A positive fraction), 100ng of RNA was used for library construction using TrueSeq Stranded mRNA Sample Preparation Guide, entering the protocol by adding the Fragment, Prime, Finish Mix, skipping the elution step and proceeding directly to synthesis of the First Strand cDNA. From that point on, the exact steps of the Illumina TruSeq Stranded mRNA sample Preparation Guide were followed to the end.</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <URL_LINK>
          <LABEL>GEO Sample GSM1272361</LABEL>
          <URL>http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1272361</URL>
        </URL_LINK>
      </EXPERIMENT_LINK>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>301272361</ID>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>GEO Accession</TAG>
        <VALUE>GSM1272361</VALUE>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM1272362" accession="SRX381115" center_name="GEO">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX381115</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM1272362</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM1272362: H1A T48 eluate; Homo sapiens; OTHER</TITLE>
    <STUDY_REF accession="SRP033229" refname="GSE52600">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP033229</PRIMARY_ID>
        <SUBMITTER_ID namespace="GEO">GSE52600</SUBMITTER_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS505508">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS505508</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM1272362</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>OTHER</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <SINGLE/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Cells well harvested by direct addition of TRIzol reagent (Ambion Cat.#15596018) to the cell culture plate after removal of the media and extracted using Trizol reagent protocol. Subsequently, the total RNA was DNase treated using DNase I (Promega Cat.# M610A) for 20 minutes at 37ºC followed by acid phenol/chloroform extraction, chloroform extraction and overnight NaCl2 precipitation. The precipitated RNA was washed with 70ºC ethanol and re-suspended in ultra pure H2O. RNA concentration and purity were verified by nanodrop followed by BioAnalyzer for quality control. Double polyA+ RNA selection was performed using twice Invitrogen Dynabeads mRNA Purification Kit (Cat. #610.06) protocol. RNA concentration and purity were once again verified by nanodrop followed by BioAnalyzer for quality control. For the input and post m6A-RNA IP fraction (i.e. m6A positive fraction), 100ng of RNA was used for library construction using TrueSeq Stranded mRNA Sample Preparation Guide, entering the protocol by adding the Fragment, Prime, Finish Mix, skipping the elution step and proceeding directly to synthesis of the First Strand cDNA. From that point on, the exact steps of the Illumina TruSeq Stranded mRNA sample Preparation Guide were followed to the end.</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <URL_LINK>
          <LABEL>GEO Sample GSM1272362</LABEL>
          <URL>http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1272362</URL>
        </URL_LINK>
      </EXPERIMENT_LINK>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>301272362</ID>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>GEO Accession</TAG>
        <VALUE>GSM1272362</VALUE>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM1272363" accession="SRX381116" center_name="GEO">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX381116</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM1272363</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM1272363: H1B T48 input; Homo sapiens; OTHER</TITLE>
    <STUDY_REF accession="SRP033229" refname="GSE52600">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP033229</PRIMARY_ID>
        <SUBMITTER_ID namespace="GEO">GSE52600</SUBMITTER_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS505509">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS505509</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM1272363</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>OTHER</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <SINGLE/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Cells well harvested by direct addition of TRIzol reagent (Ambion Cat.#15596018) to the cell culture plate after removal of the media and extracted using Trizol reagent protocol. Subsequently, the total RNA was DNase treated using DNase I (Promega Cat.# M610A) for 20 minutes at 37ºC followed by acid phenol/chloroform extraction, chloroform extraction and overnight NaCl2 precipitation. The precipitated RNA was washed with 70ºC ethanol and re-suspended in ultra pure H2O. RNA concentration and purity were verified by nanodrop followed by BioAnalyzer for quality control. Double polyA+ RNA selection was performed using twice Invitrogen Dynabeads mRNA Purification Kit (Cat. #610.06) protocol. RNA concentration and purity were once again verified by nanodrop followed by BioAnalyzer for quality control. For the input and post m6A-RNA IP fraction (i.e. m6A positive fraction), 100ng of RNA was used for library construction using TrueSeq Stranded mRNA Sample Preparation Guide, entering the protocol by adding the Fragment, Prime, Finish Mix, skipping the elution step and proceeding directly to synthesis of the First Strand cDNA. From that point on, the exact steps of the Illumina TruSeq Stranded mRNA sample Preparation Guide were followed to the end.</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <URL_LINK>
          <LABEL>GEO Sample GSM1272363</LABEL>
          <URL>http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1272363</URL>
        </URL_LINK>
      </EXPERIMENT_LINK>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>301272363</ID>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>GEO Accession</TAG>
        <VALUE>GSM1272363</VALUE>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM1272364" accession="SRX381117" center_name="GEO">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX381117</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM1272364</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM1272364: H1B T48 eluate; Homo sapiens; OTHER</TITLE>
    <STUDY_REF accession="SRP033229" refname="GSE52600">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP033229</PRIMARY_ID>
        <SUBMITTER_ID namespace="GEO">GSE52600</SUBMITTER_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS505510">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS505510</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM1272364</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>OTHER</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <SINGLE/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Cells well harvested by direct addition of TRIzol reagent (Ambion Cat.#15596018) to the cell culture plate after removal of the media and extracted using Trizol reagent protocol. Subsequently, the total RNA was DNase treated using DNase I (Promega Cat.# M610A) for 20 minutes at 37ºC followed by acid phenol/chloroform extraction, chloroform extraction and overnight NaCl2 precipitation. The precipitated RNA was washed with 70ºC ethanol and re-suspended in ultra pure H2O. RNA concentration and purity were verified by nanodrop followed by BioAnalyzer for quality control. Double polyA+ RNA selection was performed using twice Invitrogen Dynabeads mRNA Purification Kit (Cat. #610.06) protocol. RNA concentration and purity were once again verified by nanodrop followed by BioAnalyzer for quality control. For the input and post m6A-RNA IP fraction (i.e. m6A positive fraction), 100ng of RNA was used for library construction using TrueSeq Stranded mRNA Sample Preparation Guide, entering the protocol by adding the Fragment, Prime, Finish Mix, skipping the elution step and proceeding directly to synthesis of the First Strand cDNA. From that point on, the exact steps of the Illumina TruSeq Stranded mRNA sample Preparation Guide were followed to the end.</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <URL_LINK>
          <LABEL>GEO Sample GSM1272364</LABEL>
          <URL>http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1272364</URL>
        </URL_LINK>
      </EXPERIMENT_LINK>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>301272364</ID>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>GEO Accession</TAG>
        <VALUE>GSM1272364</VALUE>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM1272365" accession="SRX381118" center_name="GEO">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX381118</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM1272365</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM1272365: H1A T0 input (new run); Homo sapiens; OTHER</TITLE>
    <STUDY_REF accession="SRP033229" refname="GSE52600">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP033229</PRIMARY_ID>
        <SUBMITTER_ID namespace="GEO">GSE52600</SUBMITTER_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS505511">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS505511</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM1272365</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>OTHER</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <SINGLE/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Cells well harvested by direct addition of TRIzol reagent (Ambion Cat.#15596018) to the cell culture plate after removal of the media and extracted using Trizol reagent protocol. Subsequently, the total RNA was DNase treated using DNase I (Promega Cat.# M610A) for 20 minutes at 37ºC followed by acid phenol/chloroform extraction, chloroform extraction and overnight NaCl2 precipitation. The precipitated RNA was washed with 70ºC ethanol and re-suspended in ultra pure H2O. RNA concentration and purity were verified by nanodrop followed by BioAnalyzer for quality control. Double polyA+ RNA selection was performed using twice Invitrogen Dynabeads mRNA Purification Kit (Cat. #610.06) protocol. RNA concentration and purity were once again verified by nanodrop followed by BioAnalyzer for quality control. For the input and post m6A-RNA IP fraction (i.e. m6A positive fraction), 100ng of RNA was used for library construction using TrueSeq Stranded mRNA Sample Preparation Guide, entering the protocol by adding the Fragment, Prime, Finish Mix, skipping the elution step and proceeding directly to synthesis of the First Strand cDNA. From that point on, the exact steps of the Illumina TruSeq Stranded mRNA sample Preparation Guide were followed to the end.</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <URL_LINK>
          <LABEL>GEO Sample GSM1272365</LABEL>
          <URL>http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1272365</URL>
        </URL_LINK>
      </EXPERIMENT_LINK>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>301272365</ID>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>GEO Accession</TAG>
        <VALUE>GSM1272365</VALUE>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM1272366" accession="SRX381119" center_name="GEO">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX381119</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM1272366</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM1272366: H1A T0 eluate (new run); Homo sapiens; OTHER</TITLE>
    <STUDY_REF accession="SRP033229" refname="GSE52600">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP033229</PRIMARY_ID>
        <SUBMITTER_ID namespace="GEO">GSE52600</SUBMITTER_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS505512">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS505512</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM1272366</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>OTHER</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <SINGLE/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Cells well harvested by direct addition of TRIzol reagent (Ambion Cat.#15596018) to the cell culture plate after removal of the media and extracted using Trizol reagent protocol. Subsequently, the total RNA was DNase treated using DNase I (Promega Cat.# M610A) for 20 minutes at 37ºC followed by acid phenol/chloroform extraction, chloroform extraction and overnight NaCl2 precipitation. The precipitated RNA was washed with 70ºC ethanol and re-suspended in ultra pure H2O. RNA concentration and purity were verified by nanodrop followed by BioAnalyzer for quality control. Double polyA+ RNA selection was performed using twice Invitrogen Dynabeads mRNA Purification Kit (Cat. #610.06) protocol. RNA concentration and purity were once again verified by nanodrop followed by BioAnalyzer for quality control. For the input and post m6A-RNA IP fraction (i.e. m6A positive fraction), 100ng of RNA was used for library construction using TrueSeq Stranded mRNA Sample Preparation Guide, entering the protocol by adding the Fragment, Prime, Finish Mix, skipping the elution step and proceeding directly to synthesis of the First Strand cDNA. From that point on, the exact steps of the Illumina TruSeq Stranded mRNA sample Preparation Guide were followed to the end.</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <URL_LINK>
          <LABEL>GEO Sample GSM1272366</LABEL>
          <URL>http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1272366</URL>
        </URL_LINK>
      </EXPERIMENT_LINK>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>301272366</ID>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>GEO Accession</TAG>
        <VALUE>GSM1272366</VALUE>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM1272367" accession="SRX381120" center_name="GEO">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX381120</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM1272367</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM1272367: H1B T0 input (new run); Homo sapiens; OTHER</TITLE>
    <STUDY_REF accession="SRP033229" refname="GSE52600">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP033229</PRIMARY_ID>
        <SUBMITTER_ID namespace="GEO">GSE52600</SUBMITTER_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS505513">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS505513</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM1272367</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>OTHER</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <SINGLE/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Cells well harvested by direct addition of TRIzol reagent (Ambion Cat.#15596018) to the cell culture plate after removal of the media and extracted using Trizol reagent protocol. Subsequently, the total RNA was DNase treated using DNase I (Promega Cat.# M610A) for 20 minutes at 37ºC followed by acid phenol/chloroform extraction, chloroform extraction and overnight NaCl2 precipitation. The precipitated RNA was washed with 70ºC ethanol and re-suspended in ultra pure H2O. RNA concentration and purity were verified by nanodrop followed by BioAnalyzer for quality control. Double polyA+ RNA selection was performed using twice Invitrogen Dynabeads mRNA Purification Kit (Cat. #610.06) protocol. RNA concentration and purity were once again verified by nanodrop followed by BioAnalyzer for quality control. For the input and post m6A-RNA IP fraction (i.e. m6A positive fraction), 100ng of RNA was used for library construction using TrueSeq Stranded mRNA Sample Preparation Guide, entering the protocol by adding the Fragment, Prime, Finish Mix, skipping the elution step and proceeding directly to synthesis of the First Strand cDNA. From that point on, the exact steps of the Illumina TruSeq Stranded mRNA sample Preparation Guide were followed to the end.</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <URL_LINK>
          <LABEL>GEO Sample GSM1272367</LABEL>
          <URL>http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1272367</URL>
        </URL_LINK>
      </EXPERIMENT_LINK>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>301272367</ID>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>GEO Accession</TAG>
        <VALUE>GSM1272367</VALUE>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM1272368" accession="SRX381121" center_name="GEO">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX381121</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM1272368</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM1272368: H1B T0 eluate (new run); Homo sapiens; OTHER</TITLE>
    <STUDY_REF accession="SRP033229" refname="GSE52600">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP033229</PRIMARY_ID>
        <SUBMITTER_ID namespace="GEO">GSE52600</SUBMITTER_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS505514">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS505514</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM1272368</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>OTHER</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <SINGLE/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Cells well harvested by direct addition of TRIzol reagent (Ambion Cat.#15596018) to the cell culture plate after removal of the media and extracted using Trizol reagent protocol. Subsequently, the total RNA was DNase treated using DNase I (Promega Cat.# M610A) for 20 minutes at 37ºC followed by acid phenol/chloroform extraction, chloroform extraction and overnight NaCl2 precipitation. The precipitated RNA was washed with 70ºC ethanol and re-suspended in ultra pure H2O. RNA concentration and purity were verified by nanodrop followed by BioAnalyzer for quality control. Double polyA+ RNA selection was performed using twice Invitrogen Dynabeads mRNA Purification Kit (Cat. #610.06) protocol. RNA concentration and purity were once again verified by nanodrop followed by BioAnalyzer for quality control. For the input and post m6A-RNA IP fraction (i.e. m6A positive fraction), 100ng of RNA was used for library construction using TrueSeq Stranded mRNA Sample Preparation Guide, entering the protocol by adding the Fragment, Prime, Finish Mix, skipping the elution step and proceeding directly to synthesis of the First Strand cDNA. From that point on, the exact steps of the Illumina TruSeq Stranded mRNA sample Preparation Guide were followed to the end.</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <URL_LINK>
          <LABEL>GEO Sample GSM1272368</LABEL>
          <URL>http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1272368</URL>
        </URL_LINK>
      </EXPERIMENT_LINK>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>301272368</ID>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>GEO Accession</TAG>
        <VALUE>GSM1272368</VALUE>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
</EXPERIMENT_SET>
