SRP311209 PRJNA715442 GSE169152 RNAseq_nalm6 and Sem_Asparaginase_Ibrutinib To determine how inhibition of BTK synergizes with ASNase, we performed RNA sequencing investigating which genes are affected in response to ASNase, ibrutinib or the combination Overall design: Nalm6 and Sem cells were either left untreated or treated for 24h 10um Ibrutinib, 1 IU/ml Asparaginase or a combination of both drugs. GSE169152