SRP311981 PRJNA716991 GSE169546 ST6Gal1 sialyltransferase promotes pancreatic ductal adenocarcinoma by facilitating acinar to ductal metaplasia RNA-Seq analyses of pancreata from mice with expression of the following genes: (1) "KC" mice with KRasG12D; (2) "KSC" mice with dual expression of KRasG12D and ST6Gal1 (3) "SC" mice with expression of ST6Gal1; and (4) "WT" mice representing littermate controls lacking Cre expression. Overall design: RNA was harvested from freshly-isolated pancreata from 20 week-old mice with PDX1-Cre driven expression of KRrasG12D (KC), ST6Gal1 (SC), or a combination of KRasG12D and ST6Gal (KSC). "WT" littermate controls lack PDX1-Cre GSE169546 pubmed 37643018