SRX11239195 GSM5403388 SRP325805 SRS9285680 GSM5403388 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403388 GSM5403388 GEO Accession GSM5403388 SRX11239196 GSM5403389 SRP325805 SRS9285681 GSM5403389 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403389 GSM5403389 GEO Accession GSM5403389 SRX11239197 GSM5403390 SRP325805 SRS9285682 GSM5403390 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403390 GSM5403390 GEO Accession GSM5403390 SRX11239198 GSM5403391 SRP325805 SRS9285683 GSM5403391 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403391 GSM5403391 GEO Accession GSM5403391 SRX11239199 GSM5403392 SRP325805 SRS9285684 GSM5403392 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403392 GSM5403392 GEO Accession GSM5403392 SRX11239200 GSM5403393 SRP325805 SRS9285685 GSM5403393 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403393 GSM5403393 GEO Accession GSM5403393 SRX11239201 GSM5403394 SRP325805 SRS9285686 GSM5403394 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403394 GSM5403394 GEO Accession GSM5403394 SRX11239202 GSM5403395 SRP325805 SRS9285687 GSM5403395 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403395 GSM5403395 GEO Accession GSM5403395 SRX11239203 GSM5403396 SRP325805 SRS9285688 GSM5403396 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403396 GSM5403396 GEO Accession GSM5403396 SRX11239204 GSM5403397 SRP325805 SRS9285689 GSM5403397 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403397 GSM5403397 GEO Accession GSM5403397 SRX11239205 GSM5403398 SRP325805 SRS9285690 GSM5403398 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403398 GSM5403398 GEO Accession GSM5403398 SRX11239206 GSM5403399 SRP325805 SRS9285691 GSM5403399 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403399 GSM5403399 GEO Accession GSM5403399 SRX11239207 GSM5403400 SRP325805 SRS9285692 GSM5403400 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403400 GSM5403400 GEO Accession GSM5403400 SRX11239208 GSM5403401 SRP325805 SRS9285693 GSM5403401 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403401 GSM5403401 GEO Accession GSM5403401 SRX11239209 GSM5403402 SRP325805 SRS9285694 GSM5403402 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403402 GSM5403402 GEO Accession GSM5403402 SRX11239210 GSM5403403 SRP325805 SRS9285695 GSM5403403 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403403 GSM5403403 GEO Accession GSM5403403 SRX11239211 GSM5403404 SRP325805 SRS9285696 GSM5403404 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403404 GSM5403404 GEO Accession GSM5403404 SRX11239212 GSM5403405 SRP325805 SRS9285697 GSM5403405 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403405 GSM5403405 GEO Accession GSM5403405 SRX11239213 GSM5403406 SRP325805 SRS9285698 GSM5403406 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403406 GSM5403406 GEO Accession GSM5403406 SRX11239214 GSM5403407 SRP325805 SRS9285699 GSM5403407 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403407 GSM5403407 GEO Accession GSM5403407 SRX11239215 GSM5403408 SRP325805 SRS9285700 GSM5403408 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403408 GSM5403408 GEO Accession GSM5403408 SRX11239216 GSM5403409 SRP325805 SRS9285701 GSM5403409 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403409 GSM5403409 GEO Accession GSM5403409 SRX11239217 GSM5403410 SRP325805 SRS9285702 GSM5403410 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403410 GSM5403410 GEO Accession GSM5403410 SRX11239218 GSM5403411 SRP325805 SRS9285703 GSM5403411 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403411 GSM5403411 GEO Accession GSM5403411 SRX11239219 GSM5403412 SRP325805 SRS9285704 GSM5403412 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403412 GSM5403412 GEO Accession GSM5403412 SRX11239220 GSM5403413 SRP325805 SRS9285705 GSM5403413 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403413 GSM5403413 GEO Accession GSM5403413 SRX11239221 GSM5403414 SRP325805 SRS9285706 GSM5403414 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403414 GSM5403414 GEO Accession GSM5403414 SRX11239222 GSM5403415 SRP325805 SRS9285707 GSM5403415 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403415 GSM5403415 GEO Accession GSM5403415 SRX11239223 GSM5403416 SRP325805 SRS9285708 GSM5403416 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403416 GSM5403416 GEO Accession GSM5403416 SRX11239224 GSM5403417 SRP325805 SRS9285709 GSM5403417 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403417 GSM5403417 GEO Accession GSM5403417 SRX11239225 GSM5403418 SRP325805 SRS9285710 GSM5403418 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403418 GSM5403418 GEO Accession GSM5403418 SRX11239226 GSM5403419 SRP325805 SRS9285711 GSM5403419 RNA-Seq TRANSCRIPTOMIC cDNA Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403419 GSM5403419 GEO Accession GSM5403419 SRX11239227 GSM5403420 SRP325805 SRS9285712 GSM5403420 RIP-Seq TRANSCRIPTOMIC other Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403420 GSM5403420 GEO Accession GSM5403420 SRX11239228 GSM5403421 SRP325805 SRS9285713 GSM5403421 RIP-Seq TRANSCRIPTOMIC other Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403421 GSM5403421 GEO Accession GSM5403421 SRX11239229 GSM5403422 SRP325805 SRS9285714 GSM5403422 RIP-Seq TRANSCRIPTOMIC other Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403422 GSM5403422 GEO Accession GSM5403422 SRX11239230 GSM5403423 SRP325805 SRS9285715 GSM5403423 RIP-Seq TRANSCRIPTOMIC other Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403423 GSM5403423 GEO Accession GSM5403423 SRX11239231 GSM5403424 SRP325805 SRS9285716 GSM5403424 RIP-Seq TRANSCRIPTOMIC other Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403424 GSM5403424 GEO Accession GSM5403424 SRX11239232 GSM5403425 SRP325805 SRS9285717 GSM5403425 RIP-Seq TRANSCRIPTOMIC other Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403425 GSM5403425 GEO Accession GSM5403425 SRX11239233 GSM5403426 SRP325805 SRS9285718 GSM5403426 RIP-Seq TRANSCRIPTOMIC other Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403426 GSM5403426 GEO Accession GSM5403426 SRX11239234 GSM5403427 SRP325805 SRS9285719 GSM5403427 RIP-Seq TRANSCRIPTOMIC other Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403427 GSM5403427 GEO Accession GSM5403427 SRX11239235 GSM5403428 SRP325805 SRS9285720 GSM5403428 RIP-Seq TRANSCRIPTOMIC other Degradation assay: RNA was extracted and purified using RNA isolation kit (Qiagen). RIP-Seq: The beads were mixed with RLT buffer and samples were processed according to RNA-isolation kit (Qiagen) following manufacturer's instruction. Degradation assay: Indexed RNA-Seq libraries were prepared from 500 ng total RNA using the KAPA Stranded mRNA-Seq Kit (Kapa Biosystems, Inc.) according to the manufacturer's protocol. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of 300 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. RIP-Seq: cDNA libraries for each sample were generated from total RNA using the Quantseq 3′ mRNA-Seq Library Prep kit for Illumina (Lexogen) following the manufacturer's instructions. Libraries were size-selected with SPRI beads and quantified by QuBIT (Life Technologies). Average size of ∼250 bp was determined by TapeStation (Agilent Technologies, USA). Libraries are then sequenced using an Illumina Nextseq500 sequencer. NextSeq 500 gds 305403428 GSM5403428 GEO Accession GSM5403428