SRP326946 PRJNA743790 Clinical cohorts: Diabetic microbial dysbiosis exacerbates stroke Our study focused on the association between stroke and diabetes through gut microbial dysbiosis. A clinical cohort was established and the fecal samples were collected to explore the gut microbiota composition in type 2 diabetes (T2D), acute ischemic stroke (AIS), AIS with T2D patients, and healthy controls.