<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE179582" accession="SRP327203">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP327203</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA744235</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE179582</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Genome wide maps of histone modifications in PRC2 isogenic human MPNST cells with or without DNA demethylating therapy (ChIP-Seq)</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Other"/>
      <STUDY_ABSTRACT>Goals of this study were to determine the effect of PRC2 loss or DNA demethylating therapy (GSK862 and DAC) either alone or in combination on histone modifications. Overall design: Analysis of 3 histone modifications (H3K27me3, H3K4me3, H3K27ac) in SUZ12 isogenic M3 MPNST cells treated with either Vehicle, GSK862, or DAC.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE179582</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>35789380</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
    <STUDY_ATTRIBUTES>
      <STUDY_ATTRIBUTE>
        <TAG>parent_bioproject</TAG>
        <VALUE>PRJNA744233</VALUE>
      </STUDY_ATTRIBUTE>
    </STUDY_ATTRIBUTES>
  </STUDY>
</STUDY_SET>
