SRP327878 PRJNA745501 Role of SENP7 in CD8+ T cell function in vitro Fresh splenic naive CD8+ T cells were isolated from 6-week-old Senp7fl/fl and Senp7fl/flCd4-Cre mice and stimulated with anti-CD3 and anti-CD28 for 8 hours, Activated CD8+ T cells were used for total RNA isolation with TRIzol and subjected to RNA-sequencing.