SRX12198641 ACHN-1 SRP337263 bp0 ACHN-VHL+ cells were the geniune cell line of ACHN from ATCC with crispr/cas9 vehicle control SRS10174990 ACHN-VHL+_bulk_RNAseq ACHN-1 RNA-Seq TRANSCRIPTOMIC cDNA Illumina HiSeq 3000 SRX12198642 ACHN-2 SRP337263 bp0 ACHN-VHL- cells were made by crispr/cas9 mediated knockout of VHL on the basis of ACHN-VHL+ cells SRS10174992 ACHN-VHL-_bulk_RNAseq ACHN-2 RNA-Seq TRANSCRIPTOMIC cDNA Illumina HiSeq 3000 SRX12198643 WES-loci-1 SRP337263 bp0 It's the primary tumor sample from the patient #22 in table 1 of the manuscript and it's one piece of the tumor, labeled as loci 1. SRS10174993 WES_#22_loci_1 WES-loci-1 WXS GENOMIC RANDOM Illumina NovaSeq 6000 SRX12198644 WES-loci-2 SRP337263 bp0 It's the primary tumor sample from the patient #22 in table 1 of the manuscript and it's one piece of the tumor, labeled as loci 2. SRS10174991 WES_#22_loci_2 WES-loci-2 WXS GENOMIC RANDOM Illumina NovaSeq 6000 SRX12198645 WES-loci-3 SRP337263 bp0 It's the primary tumor sample from the patient #22 in table 1 of the manuscript and it's one piece of the tumor, labeled as loci 3. SRS10174994 WES_#22_loci_3 WES-loci-3 WXS GENOMIC RANDOM Illumina NovaSeq 6000 SRX12198646 WES-loci-4 SRP337263 bp0 It's the primary tumor sample from the patient #22 in table 1 of the manuscript and it's one piece of the tumor, labeled as loci 4 SRS10174995 WES_#22_loci_4 WES-loci-4 WXS GENOMIC RANDOM Illumina NovaSeq 6000 SRX12198647 WES-cells SRP337263 bp0 It's the primary tumor sample derived cell line of patient #22 in table 1 of the manuscript and was sent for Whole exome sequencing SRS10174996 WES_#22_primary_tumor_derived_cells WES-cells WXS GENOMIC RANDOM Illumina NovaSeq 6000 SRX12198648 WES-cells-ko SRP337263 bp0 it's the crispr/cas9 mediated knockout of VHL cell line based on the primary cell line from patient #22 SRS10174997 WES_#22_primary_tumor_derived_cells_VHL- WES-cells-ko WXS GENOMIC RANDOM Illumina NovaSeq 6000 SRX12198649 scRNAseq-cells SRP337263 bp0 The primary cell line from patient #22 in table 1 from the manuscript and it was sent for single cell sequencing. SRS10174998 scRNAseq_#22_primary_tumor_derived_cells scRNAseq-cells RNA-Seq TRANSCRIPTOMIC SINGLE CELL cDNA NextSeq 500 SRX12198650 sc-nucRNAseq-tissue SRP337263 bp0 The digested tissue nuclei from the frozen stock of primary tumor from patient #22 in table 1 of the manuscript. It was sent for single cell nuclei RNAseq. SRS10174999 sc-nucRNAseq_#22_primary_tumor sc-nucRNAseq-tissue RNA-Seq TRANSCRIPTOMIC SINGLE CELL cDNA NextSeq 500