SRX12298597 GSM5593357 GSM5593357: AP.3.MF: AP treated Tumor Macrophage Cells Run 1 Rep3; Mus musculus; RNA-Seq SRP338230 SRS10272281 GSM5593357 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593357 GEO Accession GSM5593357 SRX12298598 GSM5593358 GSM5593358: AP.4.MF: AP treated Tumor Macrophage Cells Run 1 Rep4; Mus musculus; RNA-Seq SRP338230 SRS10272280 GSM5593358 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593358 GEO Accession GSM5593358 SRX12298599 GSM5593359 GSM5593359: AP.5.NK: AP treated Tumor Natural-Killer Cells Run 1 Rep5; Mus musculus; RNA-Seq SRP338230 SRS10272278 GSM5593359 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593359 GEO Accession GSM5593359 SRX12298600 GSM5593360 GSM5593360: AP.5.MF: AP treated Tumor Macrophage Cells Run 1 Rep5; Mus musculus; RNA-Seq SRP338230 SRS10272279 GSM5593360 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593360 GEO Accession GSM5593360 SRX12298601 GSM5593307 GSM5593307: AIP.T.NK.1: AIP treated Tumor Natural-Killer Cells Run 2 Rep1; Mus musculus; RNA-Seq SRP338230 SRS10272282 GSM5593307 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593307 GEO Accession GSM5593307 SRX12298602 GSM5593308 GSM5593308: AIP.T.NK.2: AIP treated Tumor Natural-Killer Cells Run 2 Rep2; Mus musculus; RNA-Seq SRP338230 SRS10272283 GSM5593308 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593308 GEO Accession GSM5593308 SRX12298603 GSM5593309 GSM5593309: AIP.T.NK.3: AIP treated Tumor Natural-Killer Cells Run 2 Rep3; Mus musculus; RNA-Seq SRP338230 SRS10272284 GSM5593309 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593309 GEO Accession GSM5593309 SRX12298604 GSM5593310 GSM5593310: UT.T.MF.1: Untreated Tumor Macrophage Cells Run 2 Rep1; Mus musculus; RNA-Seq SRP338230 SRS10272286 GSM5593310 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593310 GEO Accession GSM5593310 SRX12298605 GSM5593311 GSM5593311: UT.T.MF.2: Untreated Tumor Macrophage Cells Run 2 Rep2; Mus musculus; RNA-Seq SRP338230 SRS10272287 GSM5593311 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593311 GEO Accession GSM5593311 SRX12298606 GSM5593312 GSM5593312: UT.T.MF.3: Untreated Tumor Macrophage Cells Run 2 Rep3; Mus musculus; RNA-Seq SRP338230 SRS10272285 GSM5593312 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593312 GEO Accession GSM5593312 SRX12298607 GSM5593313 GSM5593313: AIP.T.MF.1: AIP treated Tumor Macrophage Cells Run 2 Rep1; Mus musculus; RNA-Seq SRP338230 SRS10272288 GSM5593313 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593313 GEO Accession GSM5593313 SRX12298608 GSM5593314 GSM5593314: AIP.T.MF.2: AIP treated Tumor Macrophage Cells Run 2 Rep2; Mus musculus; RNA-Seq SRP338230 SRS10272289 GSM5593314 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593314 GEO Accession GSM5593314 SRX12298609 GSM5593315 GSM5593315: AIP.T.MF.3: AIP treated Tumor Macrophage Cells Run 2 Rep3; Mus musculus; RNA-Seq SRP338230 SRS10272290 GSM5593315 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593315 GEO Accession GSM5593315 SRX12298610 GSM5593316 GSM5593316: UT.T.NK.1: Untreated Tumor Natural-Killer Cells Run 2 Rep1; Mus musculus; RNA-Seq SRP338230 SRS10272292 GSM5593316 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593316 GEO Accession GSM5593316 SRX12298611 GSM5593317 GSM5593317: UT.T.NK.2: Untreated Tumor Natural-Killer Cells Run 2 Rep2; Mus musculus; RNA-Seq SRP338230 SRS10272291 GSM5593317 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593317 GEO Accession GSM5593317 SRX12298612 GSM5593318 GSM5593318: UT.T.NK.3: Untreated Tumor Natural-Killer Cells Run 2 Rep3; Mus musculus; RNA-Seq SRP338230 SRS10272293 GSM5593318 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593318 GEO Accession GSM5593318 SRX12298613 GSM5593319 GSM5593319: UT.1.MF: Untreated Tumor Macrophage Cells Run 1 Rep1; Mus musculus; RNA-Seq SRP338230 SRS10272296 GSM5593319 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593319 GEO Accession GSM5593319 SRX12298614 GSM5593320 GSM5593320: UT.2.MF: Untreated Tumor Macrophage Cells Run 1 Rep2; Mus musculus; RNA-Seq SRP338230 SRS10272294 GSM5593320 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593320 GEO Accession GSM5593320 SRX12298615 GSM5593321 GSM5593321: UT.3.MF: Untreated Tumor Macrophage Cells Run 1 Rep3; Mus musculus; RNA-Seq SRP338230 SRS10272295 GSM5593321 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593321 GEO Accession GSM5593321 SRX12298616 GSM5593322 GSM5593322: UT.4.NK: Untreated Tumor Natural-Killer Cells Run 1 Rep4; Mus musculus; RNA-Seq SRP338230 SRS10272297 GSM5593322 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593322 GEO Accession GSM5593322 SRX12298617 GSM5593323 GSM5593323: UT.4.MF: Untreated Tumor Macrophage Cells Run 1 Rep4; Mus musculus; RNA-Seq SRP338230 SRS10272298 GSM5593323 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593323 GEO Accession GSM5593323 SRX12298618 GSM5593324 GSM5593324: UT.5.MF: Untreated Tumor Macrophage Cells Run 1 Rep5; Mus musculus; RNA-Seq SRP338230 SRS10272300 GSM5593324 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593324 GEO Accession GSM5593324 SRX12298619 GSM5593325 GSM5593325: AIP.1.MF: AIP treated Tumor Macrophage Cells Run 1 Rep1; Mus musculus; RNA-Seq SRP338230 SRS10272299 GSM5593325 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593325 GEO Accession GSM5593325 SRX12298620 GSM5593326 GSM5593326: AIP.2.NK: AIP treated Tumor Natural-Killer Cells Run 1 Rep2; Mus musculus; RNA-Seq SRP338230 SRS10272301 GSM5593326 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593326 GEO Accession GSM5593326 SRX12298621 GSM5593327 GSM5593327: AIP.3.NK: AIP treated Tumor Natural-Killer Cells Run 1 Rep3; Mus musculus; RNA-Seq SRP338230 SRS10272304 GSM5593327 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593327 GEO Accession GSM5593327 SRX12298622 GSM5593328 GSM5593328: AIP.3.MF: AIP treated Tumor Macrophage Cells Run 1 Rep3; Mus musculus; RNA-Seq SRP338230 SRS10272303 GSM5593328 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593328 GEO Accession GSM5593328 SRX12298623 GSM5593329 GSM5593329: AIP.4.NK: AIP treated Tumor Natural-Killer Cells Run 1 Rep4; Mus musculus; RNA-Seq SRP338230 SRS10272302 GSM5593329 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593329 GEO Accession GSM5593329 SRX12298624 GSM5593330 GSM5593330: AIP.4.MF: AIP treated Tumor Macrophage Cells Run 1 Rep4; Mus musculus; RNA-Seq SRP338230 SRS10272305 GSM5593330 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593330 GEO Accession GSM5593330 SRX12298625 GSM5593331 GSM5593331: AIP.5.NK: AIP treated Tumor Natural-Killer Cells Run 1 Rep5; Mus musculus; RNA-Seq SRP338230 SRS10272306 GSM5593331 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593331 GEO Accession GSM5593331 SRX12298626 GSM5593332 GSM5593332: AIP.5.MF: AIP treated Tumor Macrophage Cells Run 1 Rep5; Mus musculus; RNA-Seq SRP338230 SRS10272307 GSM5593332 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593332 GEO Accession GSM5593332 SRX12298627 GSM5593333 GSM5593333: AI.1.NK: AI treated Tumor Natural-Killer Cells Run 1 Rep1; Mus musculus; RNA-Seq SRP338230 SRS10272308 GSM5593333 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593333 GEO Accession GSM5593333 SRX12298628 GSM5593334 GSM5593334: AI.1.MF: AI treated Tumor Macrophage Cells Run 1 Rep1; Mus musculus; RNA-Seq SRP338230 SRS10272310 GSM5593334 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593334 GEO Accession GSM5593334 SRX12298629 GSM5593335 GSM5593335: AI.2.NK: AI treated Tumor Natural-Killer Cells Run 1 Rep2; Mus musculus; RNA-Seq SRP338230 SRS10272309 GSM5593335 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593335 GEO Accession GSM5593335 SRX12298630 GSM5593336 GSM5593336: AI.2.MF: AI treated Tumor Macrophage Cells Run 1 Rep2; Mus musculus; RNA-Seq SRP338230 SRS10272312 GSM5593336 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593336 GEO Accession GSM5593336 SRX12298631 GSM5593337 GSM5593337: AI.3.NK: AI treated Tumor Natural-Killer Cells Run 1 Rep3; Mus musculus; RNA-Seq SRP338230 SRS10272311 GSM5593337 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593337 GEO Accession GSM5593337 SRX12298632 GSM5593338 GSM5593338: AI.3.MF: AI treated Tumor Macrophage Cells Run 1 Rep3; Mus musculus; RNA-Seq SRP338230 SRS10272313 GSM5593338 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593338 GEO Accession GSM5593338 SRX12298633 GSM5593339 GSM5593339: AI.4.NK: AI treated Tumor Natural-Killer Cells Run 1 Rep4; Mus musculus; RNA-Seq SRP338230 SRS10272314 GSM5593339 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593339 GEO Accession GSM5593339 SRX12298634 GSM5593340 GSM5593340: AI.4.MF: AI treated Tumor Macrophage Cells Run 1 Rep4; Mus musculus; RNA-Seq SRP338230 SRS10272316 GSM5593340 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593340 GEO Accession GSM5593340 SRX12298635 GSM5593341 GSM5593341: AI.5.NK: AI treated Tumor Natural-Killer Cells Run 1 Rep5; Mus musculus; RNA-Seq SRP338230 SRS10272315 GSM5593341 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593341 GEO Accession GSM5593341 SRX12298636 GSM5593342 GSM5593342: AI.5.MF: AI treated Tumor Macrophage Cells Run 1 Rep5; Mus musculus; RNA-Seq SRP338230 SRS10272317 GSM5593342 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593342 GEO Accession GSM5593342 SRX12298637 GSM5593343 GSM5593343: IP.1.NK: IP treated Tumor Natural-Killer Cells Run 1 Rep1; Mus musculus; RNA-Seq SRP338230 SRS10272318 GSM5593343 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593343 GEO Accession GSM5593343 SRX12298638 GSM5593344 GSM5593344: IP.1.MF: IP treated Tumor Macrophage Cells Run 1 Rep1; Mus musculus; RNA-Seq SRP338230 SRS10272319 GSM5593344 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593344 GEO Accession GSM5593344 SRX12298639 GSM5593345 GSM5593345: IP.2.NK: IP treated Tumor Natural-Killer Cells Run 1 Rep2; Mus musculus; RNA-Seq SRP338230 SRS10272320 GSM5593345 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593345 GEO Accession GSM5593345 SRX12298640 GSM5593346 GSM5593346: IP.2.MF: IP treated Tumor Macrophage Cells Run 1 Rep2; Mus musculus; RNA-Seq SRP338230 SRS10272321 GSM5593346 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593346 GEO Accession GSM5593346 SRX12298641 GSM5593347 GSM5593347: IP.3.NK: IP treated Tumor Natural-Killer Cells Run 1 Rep3; Mus musculus; RNA-Seq SRP338230 SRS10272322 GSM5593347 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593347 GEO Accession GSM5593347 SRX12298642 GSM5593348 GSM5593348: IP.3.MF: IP treated Tumor Macrophage Cells Run 1 Rep3; Mus musculus; RNA-Seq SRP338230 SRS10272323 GSM5593348 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593348 GEO Accession GSM5593348 SRX12298643 GSM5593349 GSM5593349: IP.4.NK: IP treated Tumor Natural-Killer Cells Run 1 Rep4; Mus musculus; RNA-Seq SRP338230 SRS10272324 GSM5593349 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593349 GEO Accession GSM5593349 SRX12298644 GSM5593350 GSM5593350: IP.4.MF: IP treated Tumor Macrophage Cells Run 1 Rep4; Mus musculus; RNA-Seq SRP338230 SRS10272325 GSM5593350 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593350 GEO Accession GSM5593350 SRX12298645 GSM5593351 GSM5593351: IP.5.NK: IP treated Tumor Natural-Killer Cells Run 1 Rep5; Mus musculus; RNA-Seq SRP338230 SRS10272326 GSM5593351 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593351 GEO Accession GSM5593351 SRX12298646 GSM5593352 GSM5593352: IP.5.MF: IP treated Tumor Macrophage Cells Run 1 Rep5; Mus musculus; RNA-Seq SRP338230 SRS10272327 GSM5593352 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593352 GEO Accession GSM5593352 SRX12298647 GSM5593353 GSM5593353: AP.1.MF: AP treated Tumor Macrophage Cells Run 1 Rep1; Mus musculus; RNA-Seq SRP338230 SRS10272328 GSM5593353 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593353 GEO Accession GSM5593353 SRX12298648 GSM5593354 GSM5593354: AP.2.NK: AP treated Tumor Natural-Killer Cells Run 1 Rep2; Mus musculus; RNA-Seq SRP338230 SRS10272330 GSM5593354 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593354 GEO Accession GSM5593354 SRX12298649 GSM5593355 GSM5593355: AP.2.MF: AP treated Tumor Macrophage Cells Run 1 Rep2; Mus musculus; RNA-Seq SRP338230 SRS10272329 GSM5593355 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593355 GEO Accession GSM5593355 SRX12298650 GSM5593356 GSM5593356: AP.3.NK: AP treated Tumor Natural-Killer Cells Run 1 Rep3; Mus musculus; RNA-Seq SRP338230 SRS10272331 GSM5593356 RNA-Seq TRANSCRIPTOMIC cDNA Tumor samples were collected immediately after surgery and submerged in tissue storage solution and were dissociated using the mouse tumor dissociation kit. Briefly, tumors were cut into small pieces (~ 2-4 mm3) and transferred to a gentle MACS C tube containing 2.35 ml RPMI 1640, 100 μl Enzyme D, 50 μl Enzyme R and 12.5 μl Enzyme A. The program 37C_m_TDK_1 was used on a gentle MACS Octo Dissociator with Heaters to fully dissociate tumor tissue. After digestion, the solution was diluted in 10 ml RPMI 1640 and filtered through a prewetted 70 μm filter. Cells were pelleted and used for positive selection of immune cells using mouse CD45 MicroBeads. RNA libraries were prepared for sequencing using SMART-Seq v2 protocol for Illumina Illumina HiSeq 2000 gds 305593356 GEO Accession GSM5593356