SRP342169 PRJNA772760 GSE186164 Single-cell Gene expression of WT CD8aa IEL and LRF-deficient CD8aa splenocytes To examine how the cluster composition of CD8aa IEL and their transcriptomic signatures were affected by LRF disruption, single-cell gene expression of CD8aa IEL from control (Cd4 Cre–Lrffl/fl) and CD8aa splenocytes from LRF KO (Cd4 Cre+Lrffl/fl ) mice were determined by scRNAseq. Overall design: CD8aa IEL from control (Cd4 Cre–Lrffl/fl) and CD8aa splenocytes from LRF KO(Cd4 Cre+Lrffl/fl ) mice were sorted, and their gene expression was determined by scRNAseq. GSE186164 pubmed 35354951