<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE186225" accession="SRP342298">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP342298</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA773044</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE186225</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>CUT-tag analysis of T24 cells treated with a control scramble (scr) siRNA or a si-circSLC38A1</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Other"/>
      <STUDY_ABSTRACT>This study aims to investigate whether circSLC38A1 could affect the enrichment of downstream genes by the transcription factor ILF3.T24 cells were treated with a control scramble (scr) siRNA or a siRNA that specifically knock down the expression of circSLC38A1, 48h after ttansfection, cells were collected and treated for CUT-tag.CUT-tag-Seq analysis provided evidence of ILF3 enrichment of downstream genes changes between si-NC and si-circSLC38A1 T24 cells. Overall design: Cells were treated with a control scramble (scr) siRNA or a siRNA that specifically knock down the expression of circSLC38A1.Peaks bound by ILF3 were obtained using CUT-tag-Seq.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE186225</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>36697384</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
  </STUDY>
</STUDY_SET>
